Systematic Use of Germane Ancillary Results to Clarify Optimal Antidiabetic Therapies after Stroke (Sugar-Coats): Randomized Controlled Trials

Lee, Meng (PI)
Chen, Yu-Wei (CoPI)
Hsieh, Chengyang (CoPI)
Hsu, Chia Yu (CoPI)
Huang, Yen-Chu (CoPI)
Huang, Wen Yi (CoPI)
Jeng, Jiann Shing (CoPI)
Lee, Jiann-Der (CoPI)
Lin, Chunhsien (CoPI)
Liu, Chi Hung (CoPI)
Peng, Yun Shing (CoPI)
Sung, Sheng Feng (CoPI)
Tang, Sung Chun (CoPI)

School of Medicine

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Abstract

高敏感 CRP (hs-CRP) 是個發炎的指標，其數值是心血管疾病的獨立預測因子，因此可被用來當作未來心血管事件的替代指標。BNP 則是左心室功能的指標。合併使用 metformin, pioglitazone, SGLT-2 抑制劑 (empagliflozin or dapagliflozin or canagliflozin) 三種藥物治療 6 個月如果可以在中風且有糖尿病的病患能降低 hs-CRP 與 BNP 等指標，代表這樣的組合可降低發炎與並可能改善左心室功能，可作為這族群血糖控制的優先療法。

Project IDs

Project ID:PC11007-1384
External Project ID:MOST110-2314-B182-036-MY2

Status	Finished
Effective start/end date	01/08/21 → 31/07/22

Keywords

ischemic stroke
diabetes mellitus
pioglitazone
SGLT-2 inhibitor
hs-CRP

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https://www.grb.gov.tw/search/planDetail?id=13874741

Systematic Use of Germane Ancillary Results to Clarify Optimal Antidiabetic Therapies after Stroke (Sugar-Coats): Randomized Controlled Trials

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Abstract

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Keywords

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