The Aerobic Exercise-Induced Epigenetic Adaptations in Cardiomyocytes

Project: National Science and Technology CouncilNational Science and Technology Council Academic Grants

Project Details

Abstract

由之前的研究發現有氧運動會影響⼼臟的⽣理功能,因此我們建⽴運動訓練對⼼肌母細胞影響的細胞模型。透過⽐對細胞學與臨床檢查結果,評估不同的有氧運動可能影響⼼肌細胞內的蛋白質體,與表觀遺傳,來延長有氧運動對心臟的影響期限。透過基因甲基化分析,找到心肌細胞對運動的表觀遺傳適應,以做為對健康人與心臟病患精確運動處⽅的依據。透過適當的運動,增進人類的健康,並降低醫療費⽤。

Project IDs

Project ID:PC11008-0174
External Project ID:MOST109-2314-B182-026-MY3
StatusFinished
Effective start/end date01/08/2131/07/22

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