The Design and Development of a Multi-Channel Accelerometer-Based Motion Sensing System and Method on the Diagnosis Assistance for Valvular Heart Diseases and the Evaluation of Its Clinical Applications (II-III)

Most of the symptoms of Valvular heart disease in early stage are not heart related. Therefore, patients tend to ignore about the symptoms or be mis-diagnosed in this stage. As a result, severe damage to the heart is caused by the long time mal-function of the heart valves and may even cause the death. However, the vibrations generated by heart valve opening/closing and blood striking against blood vessels during the periodic heart beats are essentially physical activities. It can be detected by the accelerometer-based inertial motion sensing techniques. Furthermore, the system can be realized as a simple, efficient, and adequate device for home usage, so that it can be a diagnosis assistance and treatment assessment tool to assist the patients diagnosed with suffering of the Valvular heart diseases and congestive heart failure as soon as possible. Accordingly, the purpose of this proposal is to continue the on-going study of the project approved at 2014 for two more years of study. In these two years, with the coordination of a clinical research project to define the occurrence parameters of irregular heart valve behavior in multi-channel Mechanocardiography (MCG) by testing of the patients with Valvular heart diseases and congestive heart failure. An algorithm and treatment assessment method will be developed to identify these diseases. The system will also be realized as a real-time, wireless, and portable multi-channel MCG synchronous measurement device, so that it can provide more accurate and quantitative data on diagnosis assistance and treatment assessment of the Valvular heart diseases and congestive heart failure. The system will be also validated with standard clinical techniques to evaluate its accuracy, reliability and effectiveness. Eventually, the system can be translated to clinical applications in clinical institutes or at homes. The system carries advantages of low cost, easy usage and quantified assessment. It can be further applied as a routine medical care and clinical tool for patients with Valvular heart diseases and congestive heart failure at anytime, anywhere in clinical institutes. It can also be used at homes to help patients diagnosed with suffering of the diseases earlier and have the treatments earlier. With this research, we will become the pioneers of adopting multi-channel MCG measurement in the diagnosis assistances of Valvular heart diseases and congestive heart failure in the world. It will also be a great advance of medical device industry.

Project ID:PB10408-5713
External Project ID:MOST104-2221-E182-013