The Mechanism of Microglia-Derived Exosomes on Radiation-Induced Brain Tumor Invasiveness

Yu, Ching-Fang (PI)
Cheng, Wei Chung (CoPI)
Wang, Chun-Chieh (CoPI)

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Abstract

臨床上腦癌治療效果未能有效提升主要是由於腫瘤本身對放、化療具高度抗性以及放療後所誘發的腫瘤侵襲力提升。經由了解照射後微膠細胞所分泌的外泌體增強腫瘤侵襲力及提升輻射抗性的機制，未來可應用於臨床腦癌放射治療時合併使用抑制劑，將可減弱放射後腫瘤侵襲能力，提升放射治療的成效。

Project IDs

Project ID:PC11107-5816
External Project ID:MOST110-2314-B182-060-MY2

Status	Finished
Effective start/end date	01/08/22 → 31/07/23

Access Project

https://www.grb.gov.tw/search/planDetail?id=14514423