The Molecular Characterization of Evolutionarily Conserved Immune Cell Populations and Immune Mediators in Invertebrates

Project: National Science and Technology CouncilNational Science and Technology Council Academic Grants

Project Details

Abstract

本研究之執行,對於後天免疫立如何在先天免疫存在的基礎上演化而成會有更根本的了解。這對於先天和後天免疫系統如何合作以抵抗入侵之病原會有很大的幫助,也可能會引領我們發現新的免疫治療標靶。研究執行過程中,也會訓練年輕有至於免疫學研究之學生,未來能夠投入台灣的新興生技產業中。

Project IDs

Project ID:PC11008-0828
External Project ID:MOST108-2320-B182-018-MY3
StatusFinished
Effective start/end date01/08/2131/07/22

Keywords

  • Innate immunity
  • evolution
  • invertebrates
  • cytidine deaminase
  • AID
  • APOBEC
  • somatic hypermutation
  • pyroptosis
  • gasdermin

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