The Role of Npff/Npffr2 on the Modulation of Metabolic Health: from Central to Peripheral System

  • Lin, Ya-Tin (PI)

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Project Details

Abstract

隨著近年NPFF的研究越來越多元豐富，其功能也越趨重要。前期與初步結果顯示NPFF會調控下視丘胰島素控制的攝食訊息，對能量恆定與代謝扮演重要角色，使他成為重要的目標，包括糖尿病和飲食控制。現在社會中肥胖和代謝症候群是許多疾病的高風險因子，因此NPFF的研究對社會健康層面將有很大助益。本計畫將會發展NPFF受體專一性藥物，將對NPFF相關領域的研究具有很大的幫助，並有機會發展成臨床用藥，可申請專利並進入臨床試驗研究。

Project IDs

Project ID:PC11007-1489
External Project ID:MOST110-2326-B182-002-MY3
StatusFinished
Effective start/end date01/08/21 → 31/07/22

Keywords

  • Neuropeptide FF
  • NPFFR2
  • hypothalamus
  • transgenic mice
  • knockout mice
  • energy metabolism
  • Insulin

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