The Study of the Roles of Sphingolipid Metabolic Reprogramming in Enteroviral Replication

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Project Details

Abstract

儘管 COVID-19 大流行被宣布不再是國際關注的突發公共衛生事件，但嚴重急性呼吸道症候群冠狀病毒2 (SARS-CoV2)與其它潛在新興病毒仍然對公共衛生系統構成威脅。闡明RNA病毒誘導之脂質代謝重編程及其機制對病毒學基礎知識有所裨益，尤其是宿主與病毒相互作用方面知識。它還為尋找未知的抗病毒藥物標靶分子開闢嶄新途徑，且加速藥物開發進程。本計畫研究發現並不侷限於腸病毒，尚可適用於其它 RNA 病毒。

Project IDs

Project ID:PC11307-1237
External Project ID:NSTC113-2320-B182-018-MY3
StatusFinished
Effective start/end date01/08/24 → 31/07/25

Keywords

  • enterovirus D68
  • metabolomics
  • sphingolipid

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