Therapeutic Potential and Mechanisms of Targeting Cochlear Toll-Like Receptor 9 in Noise-Induced Hearing Loss

Project: National Science and Technology CouncilNational Science and Technology Council Academic Grants

Project Details

Abstract

對於噪音性聽損,目前臨床上並無適合的藥物來預防及治療,聽損對於個人及社會之影響甚鉅,因此亟需發展有效的治療方式。尤其對於經常接受噪音暴露的軍人以及高雄在地工廠的勞工,噪音性聽損是很常見的職業傷害。若本計畫的動物模式證實能藉由針對類鐸受體9來減少聽力損傷,將有助於未來人體臨床試驗之進一步探討及發展新的治療藥物。

Project IDs

Project ID:PC11308-3456
External Project ID:NSTC111-2314-B182-072-MY3
StatusActive
Effective start/end date01/08/2431/07/25

Keywords

  • Toll-like receptor 9
  • cochlea
  • noise
  • hearing loss

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