Using Conditional Gene Knockout Mice to Study the Importance of Ddx3x in Oogenesis

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Project Details

Abstract

本計畫是研究DDX3X基因在雌性卵巢發育和卵子發生的重要性, 並且探討其分子作用機制。目前台灣的生育率下降, 不孕人口逐年增加, 少子化問題嚴重影響社會經濟及國家安全, 我們的研究成果將有助於了解部分女性不孕的原因, 提供這些不孕症患者新的治療策略。

Project IDs

Project ID:PC11207-1388
External Project ID:NSTC112-2320-B182-014
StatusFinished
Effective start/end date01/08/23 → 31/07/24

Keywords

  • Human DDX3
  • DEAD-box RNA helicase
  • translational control
  • oogenesis
  • conditional knockout mice

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