Verify the Expressions of Glucose-Regulated Genes and Their Functions and Molecular Mechanisms in the Human Bladder Stroma and Carcinoma Cells

Juang, Horng-Heng (PI)
Feng, Tsui-Hsia (CoPI)
Hou, Chen Pang (CoPI)

Project: National Science and Technology Council › National Science and Technology Council Academic Grants

Abstract

膀胱纖維化與癌化是國人重大疾病。計畫主要將模擬糖尿病下高糖尿對膀胱基質與癌細胞之影響。藉由探討4個葡萄糖調控基因之表現，功能與調控機制於人類膀胱細胞來探索與人類膀胱纖維化與癌化有關之因子。經由對葡萄糖調控基因之研究，期能抑制膀胱纖維化與癌化之形成，並提供新的藥物篩檢因子與有關膀胱疾病診斷與治療方向。

Project IDs

Project ID:PC11207-1416
External Project ID:NSTC112-2320-B182-028

Status	Finished
Effective start/end date	01/08/23 → 31/07/24

Keywords

bladder
glucose
ChREBP
ATF3
WISP1
GDF15
tumorigenesis
fibrosis

Access Project

https://www.grb.gov.tw/search/planDetail?id=15460410

Verify the Expressions of Glucose-Regulated Genes and Their Functions and Molecular Mechanisms in the Human Bladder Stroma and Carcinoma Cells

Project Details

Abstract

Project IDs

Keywords

Access Project

Fingerprint