判斷一目標生物分子是否存在於一待測樣本中的量測裝置及方法

A device for detecting existence of a target biomolecule in a specimen comprises a carrier, an irradiation unit and a reception processing unit. The carrier has at least one groove with a surface for immobilization of the specimen. The irradiation unit generates an incident light with an optical field strength changing with the time or generates a laser with parallel high coherence dual frequency linearly-polarized directions, and directs the incident light directly to the groove; thus, for the target biomolecule, if any, in the specimen, metal nanoparticle surface localized plasmon electric field of the specimen can be excited to induce the generation of strength-modulated fluorescent signal of fluorescent molecules. The signal reception processing unit is used to receive the fluorescent signal and detecting accordingly the existence of the target biomolecule in the specimen.