判斷轉移性大腸直腸癌風險、預後程度的方法及其生物標記

Jau-Song Yu; Bertrand Chin-Ming Tan; Hsuan Liu; Chia-Yu Yang; Ian Yi-Feng Chang; Chi Yang; YI-TUNG CHEN; HUNG-CHIH HSU; YING-YU LAI; YU-HAO LIU; CHUNG-PEI MA; WEN-SY TSAI; CHAN-KENG YANG

判斷轉移性大腸直腸癌風險、預後程度的方法及其生物標記

Translated title of the contribution: METHOD AND BIOMARKERS FOR ASSESSING THE RISK AND PROGNOSIS OF METASTATIC COLORECTAL CANCER

Jau-Song Yu (Inventor)
, Bertrand Chin-Ming Tan (Inventor)
, Hsuan Liu (Inventor)
, Chia-Yu Yang (Inventor)
, Ian Yi-Feng Chang (Inventor)
, Chi Yang (Inventor)
, YI-TUNG CHEN (Inventor)
, HUNG-CHIH HSU (Inventor)
, YING-YU LAI (Inventor)
, YU-HAO LIU (Inventor)
, CHUNG-PEI MA (Inventor)
, WEN-SY TSAI (Inventor)
, CHAN-KENG YANG (Inventor)

Research output: Patent

Abstract

This invention unveils a method and associated biomarkers for assessing the risk and prognostic level of metastatic colorectal cancer. The evaluation is made by observing the expression levels of EV-miR-320c in extracellular vesicles (EV), identified as the biomarker in this invention. This measure helps determine the risk of an individual developing metastatic colorectal cancer. Furthermore, post-treatment, the expression levels of EV-miR-320c in EVs can be used to monitor the progression of the disease. The detection and monitoring methodology leveraging EV-miR-320c in EVs demonstrated high sensitivity and specificity.

Translated title of the contribution	METHOD AND BIOMARKERS FOR ASSESSING THE RISK AND PROGNOSIS OF METASTATIC COLORECTAL CANCER
Original language	Chinese (Traditional)
IPC	C12Q 1/6886(2018.01)
State	Published - 16 01 2025

Bibliographical note

公開公告號: 202503070
Announcement ID: 202503070

Cite this

@misc{9e4e992048cc4e1fbd89ddb2f4148440,

title = "判斷轉移性大腸直腸癌風險、預後程度的方法及其生物標記",

abstract = "本發明揭示了一種判斷轉移性大腸直腸癌風險、預後程度的方法及其生物標記。藉由胞外囊泡中EV-miR-320c(為本發明之生物標記)的表現量來判斷檢測對象具有罹患轉移性大腸直腸癌之風險，以及當檢測對象接受治療後，也可藉由胞外囊泡中EV-miR-320c的表現量來監測預後程度。而此利用胞外囊泡中EV-miR-320c進行檢測、監控的方法，具有良好的靈敏度及特異度。",

author = "Jau-Song Yu and Tan, \{Bertrand Chin-Ming\} and Hsuan Liu and Chia-Yu Yang and Chang, \{Ian Yi-Feng\} and Chi Yang and YI-TUNG CHEN and HUNG-CHIH HSU and YING-YU LAI and YU-HAO LIU and CHUNG-PEI MA and WEN-SY TSAI and CHAN-KENG YANG",

note = "C12Q 1/6886(2018.01)",

year = "2025",

month = jan,

day = "16",

language = "繁體中文",

type = "Patent",

}

TY - PAT

T1 - 判斷轉移性大腸直腸癌風險、預後程度的方法及其生物標記

AU - Yu, Jau-Song

AU - Tan, Bertrand Chin-Ming

AU - Liu, Hsuan

AU - Yang, Chia-Yu

AU - Chang, Ian Yi-Feng

AU - Yang, Chi

AU - CHEN, YI-TUNG

AU - HSU, HUNG-CHIH

AU - LAI, YING-YU

AU - LIU, YU-HAO

AU - MA, CHUNG-PEI

AU - TSAI, WEN-SY

AU - YANG, CHAN-KENG

N1 - 公開公告號: 202503070 Announcement ID: 202503070

PY - 2025/1/16

Y1 - 2025/1/16

N2 - 本發明揭示了一種判斷轉移性大腸直腸癌風險、預後程度的方法及其生物標記。藉由胞外囊泡中EV-miR-320c(為本發明之生物標記)的表現量來判斷檢測對象具有罹患轉移性大腸直腸癌之風險，以及當檢測對象接受治療後，也可藉由胞外囊泡中EV-miR-320c的表現量來監測預後程度。而此利用胞外囊泡中EV-miR-320c進行檢測、監控的方法，具有良好的靈敏度及特異度。

AB - 本發明揭示了一種判斷轉移性大腸直腸癌風險、預後程度的方法及其生物標記。藉由胞外囊泡中EV-miR-320c(為本發明之生物標記)的表現量來判斷檢測對象具有罹患轉移性大腸直腸癌之風險，以及當檢測對象接受治療後，也可藉由胞外囊泡中EV-miR-320c的表現量來監測預後程度。而此利用胞外囊泡中EV-miR-320c進行檢測、監控的方法，具有良好的靈敏度及特異度。

M3 - 專利

ER -

判斷轉移性大腸直腸癌風險、預後程度的方法及其生物標記

Abstract

Bibliographical note

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Cite this