Abstract
一位50歲的女性在其右手背上出現了一個紅色，沒有症狀的腫塊已經有20多年了
。1997年四月她到門疹求診。臨床上病灶底部大約1～2公分直徑，堅硬結實但並未和深部組織
固定。顯微鏡下可見到雙相型結構，即周圍由許多梭狀細胞組成的真皮結節和中央由類似血
管旁細胞組成的區域。基於此種特別的病理特徵，可以確定診斷為單一性肌肉纖維瘤。特殊
染色和免疫組織化學研究包括pan-actin，vimetin和desmin染色也可符合這個診斷。
A 50-year-old woman presented with a reddish, asymptomatic lump on her right dorsal hand for more than 20 years. She visited our OPD in April 1997. Clinically the base of the lesion was about 1-2 cm in diameter, firm, and hard but not fixed with deep tissue. Microscopically, it showed biphasic pattern of multiple peripheral nodules which were composed of elongated spindle cells and central vascular structure which was composed of hemangiopericytoma-like cells. Based on the unique histopathological findings, the diagnosis of solitary myofibroma was confirmed. The results of special stain and immunohistochemical studies including pan-actin, vimetin and desmin stain were also consistent with the diagnosis.
A 50-year-old woman presented with a reddish, asymptomatic lump on her right dorsal hand for more than 20 years. She visited our OPD in April 1997. Clinically the base of the lesion was about 1-2 cm in diameter, firm, and hard but not fixed with deep tissue. Microscopically, it showed biphasic pattern of multiple peripheral nodules which were composed of elongated spindle cells and central vascular structure which was composed of hemangiopericytoma-like cells. Based on the unique histopathological findings, the diagnosis of solitary myofibroma was confirmed. The results of special stain and immunohistochemical studies including pan-actin, vimetin and desmin stain were also consistent with the diagnosis.
| Original language | Chinese (Traditional) |
|---|---|
| Pages (from-to) | 141-146 |
| Journal | 中華皮膚科醫學雜誌 |
| Volume | 16 |
| Issue number | 2 |
| State | Published - 1998 |