Abstract
The present invention provides a biodegradable thermo-responsive hydrogel, which comprises a grafting reaction product of a biodegradable component containing plural amino groups and a thermo-responsive component containing plural carboxyl groups. The present invention also provides a drug delivery system, which contains the biodegradable thermo-responsive hydrogel as carrier and an effective treatment quantity of drug. The present invention further provides a pharmaceutical composition for treatment and/or prevention of eye diseases, which contains the biodegradable thermo-respnosive hydrogel and an effective amount of ophthalmic drug. The pharmaceutical composition may overcome the low bioavailability issue of ophthalmic drug.
| Translated title of the contribution | Biodegradable thermo-responsive hydrogel, drug delivery system having the same as carrier, and pharmaceutical composition for treatment and/or prevention of eye diseases |
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| Original language | Chinese (Traditional) |
| IPC | A61K-047/42(2006.01);A61L-027/52(2006.01);A61L-027/54(2006.01) |
| State | Published - 16 12 2012 |
Bibliographical note
公開公告號: 2.01249462E8Announcement ID: 2.01249462E8