用以吸附血液中之溶解纖維蛋白之酵素之複合物及其純化血液中溶解纖維蛋白之酵素之方法

The present invention disclosed a complex for adsorbing fibrinolytic enzymes in blood and a method for purifying fibrinolytic enzymes in blood by using the same. The method comprises the following steps: crosslinking ligands to magnetic nanoparticles with amino group or carboxyl group by catalysis of a cross linker, and the ligands can be any one of tranexamic acid, cadaverine, hexamethylene diamine and spermine; adding the complex to blood with well-mixed and incubating for a predetermined time to adsorb the fibrinolytic enzymes in blood to form a complex-fibrinolytic enzyme conjugation; applying a magnetic field to collect the complex-fibrinolytic enzyme conjugation; and separating the complex-fibrinolytic enzyme conjugation to obtain fibrinolytic enzymes.