短片段干擾ＲＮＡ（ｓｉＲＮＡ）核苷酸及其醫藥組合物及用途

Chia-Rui Shen; CHINGJEN YANG; CHAO-LIN LIU

短片段干擾ＲＮＡ（ｓｉＲＮＡ）核苷酸及其醫藥組合物及用途

Translated title of the contribution: DEVELOPMENT OF ASTHMA THERAPY WITH RAAV-MEDIATED AMCASE SHRNA

Chia-Rui Shen (Inventor), CHINGJEN YANG (Inventor), CHAO-LIN LIU (Inventor)

Department of Medical Biotechnology and Laboratory Science

Research output: Patent

Abstract

The invention provides small interfering RNA (siRNA) and their carriers that could treat asthma in mammalian through inhibiting acidic mammalian chitinase (AMCase) gene expression. The invention further provides a composition comprising siRNA of the present invention and a carrier. The invention also provides a method for treating asthma of a subject.

Translated title of the contribution	DEVELOPMENT OF ASTHMA THERAPY WITH RAAV-MEDIATED AMCASE SHRNA
Original language	Chinese (Traditional)
IPC	A61K 48/00(2006.01); C12N 15/63(2006.01); C12N 15/861(2006.01); A61P 11/06(2006.01)
State	Published - 16 07 2010

Bibliographical note

公開公告號: 2.01026334E8
Announcement ID: 2.01026334E8

Cite this

@misc{527cee6935834ba9b6467c6eedfd4276,

title = "短片段干擾ＲＮＡ（ｓｉＲＮＡ）核苷酸及其醫藥組合物及用途",

abstract = "本發明係提供利用短片段干擾RNA(siRNA)核苷酸及其載體抑制哺乳類生物之AMCase蛋白表現以治療氣喘。特定言之，本發明提供一包含上述siRNA及其載體之組合物。本發明亦進一步提供一利用上述方法治療氣喘之方法。",

author = "Chia-Rui Shen and CHINGJEN YANG and CHAO-LIN LIU",

note = "A61K 48/00(2006.01); C12N 15/63(2006.01); C12N 15/861(2006.01); A61P 11/06(2006.01)",

year = "2010",

month = jul,

day = "16",

language = "繁體中文",

type = "Patent",

}

TY - PAT

T1 - 短片段干擾ＲＮＡ（ｓｉＲＮＡ）核苷酸及其醫藥組合物及用途

AU - Shen, Chia-Rui

AU - YANG, CHINGJEN

AU - LIU, CHAO-LIN

N1 - 公開公告號: 2.01026334E8 Announcement ID: 2.01026334E8

PY - 2010/7/16

Y1 - 2010/7/16

N2 - 本發明係提供利用短片段干擾RNA(siRNA)核苷酸及其載體抑制哺乳類生物之AMCase蛋白表現以治療氣喘。特定言之，本發明提供一包含上述siRNA及其載體之組合物。本發明亦進一步提供一利用上述方法治療氣喘之方法。

AB - 本發明係提供利用短片段干擾RNA(siRNA)核苷酸及其載體抑制哺乳類生物之AMCase蛋白表現以治療氣喘。特定言之，本發明提供一包含上述siRNA及其載體之組合物。本發明亦進一步提供一利用上述方法治療氣喘之方法。

M3 - 專利

ER -

短片段干擾ＲＮＡ（ｓｉＲＮＡ）核苷酸及其醫藥組合物及用途

Abstract

Bibliographical note

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Cite this