短片段干擾RNA(siRNA)核苷酸及其醫藥組合物及用途

Translated title of the contribution: DEVELOPMENT OF ASTHMA THERAPY WITH rAAV-mediated AMCase shRNA

Chia-Rui Shen (Inventor), CHINGJEN YANG (Inventor), CHAO-LIN LIU (Inventor)

Research output: Patent

Abstract

The invention provides small interfering RNA (siRNA) and their carriers that could treat asthma in mammalian through inhibiting acidic mammalian chitinase (AMCase) gene expression. The invention further provides a composition comprising siRNA of the present invention and a carrier. The invention also provides a method for treating asthma of a subject.
Translated title of the contributionDEVELOPMENT OF ASTHMA THERAPY WITH rAAV-mediated AMCase shRNA
Original languageChinese (Traditional)
Patent numberI378800
IPCA61K 48/00(2006.01); C12N 15/63(2006.01); C12N 15/861(2006.01); A61P 11/06(2006.01)
StatePublished - 11 12 2012

Bibliographical note

公開公告號: I378800
Announcement ID: I378800

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