Abstract
The present invention discloses a method of extracting arterial input function and its application for dynamic contrast enhanced magnetic resonance imaging (DCE-MRI), which includes: firstly injecting the contrast agent into a target tissue to obtain the continuous images; obtaining the concentration-time curve of the contrast agent presented at each voxel based on the continuous images, and thus automatically estimating the purity for the tissue concentration curve of each voxel; extracting the voxel having the maximum purity to be selected as the best artery position, and then extracting the tissue concentration curve as the arterial input function; and, applying the arterial input function to a pharmacokinetics model to obtain the corresponding pharmacokinetics parameters. Thus, the present invention cannot only enhance the accuracy and reliability of derived quantitative indicators, but also enhance the efficiency of quantitative analysis.
Translated title of the contribution | Method of extracting arterial input function and its application for dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) |
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Original language | Chinese (Traditional) |
IPC | A61B 5/055(2006.01) |
State | Published - 01 03 2014 |
Bibliographical note
公開公告號: 2.01408262E8Announcement ID: 2.01408262E8