非政府組織大規模肝炎社區篩檢的未滿足的需求

Community hepatitis screening promoted by non-government organizations (NGOs) is different from largescale planned inspections, which are usually conducted in a single and fixed-point manner. This study uses the results of a single community liver disease screening to assess whether there are unmet needs for community screening. This is a cross-sectional community two-stage hepatitis screening conducted by two NGOs in Daliao District, Kaohsiung City. The serum examination is performed in the first stage to test HBsAg, Anti-HCV, AFP, ALT and AST; HBV DNA and HBeAg are added to those who are HBsAg positive, and HCV RNA is added to those who are anti-HCV positive. In addition, the REACH-B risk score is used to predict the risk of liver cancer In the future for HBsAg-positive people. In the second stage, people who are HBsAg, Anti-HCV positive and AFP>20 ng/ml will be recalled for upper abdominal ultrasound examination. 1495 people were examined and 1276 were residents in Daliao District, Kaohsiung City, accounting for 11.9% of the total population of the district. The positive rates of HBsAg and anti-HCV were 9.7-12.9% and 2.3-6.5%, respectively. Of the 173 HBsAg-positive cases in the screening, 165 (95.4%) could detect HBV DNA, including 77 (44.5%) HBV DNA>2, 000 lU/ml, 38 (22.0%) HBV DNA>20, 000 lU/ml. 22 of 56 anti-HCV positive patients (39.3%) can detect HCV RNA. There were 5 patients with AFP >20 ng/ml and no new cases of liver cancer were found. In addition, 16 (9.2%) HBsAg-positive people predicted the high risk of liver cancer in ten years through REACH-B risk score.