12-epi-fragilide G, a new briarane-type diterpenoid from the gorgonian coral Ellisella robusta

Yu Chia Chang; Tsong Long Hwang; Sheng Kai Huang; Li Wan Huang; Mei Ru Lin; Ping Jyun Sung

doi:10.3987/COM-09-11899

12-epi-fragilide G, a new briarane-type diterpenoid from the gorgonian coral Ellisella robusta

Yu Chia Chang^*, Tsong Long Hwang, Sheng Kai Huang, Li Wan Huang, Mei Ru Lin, Ping Jyun Sung

^*Corresponding author for this work

School of Traditional Chinese Medicine

Research output: Contribution to journal › Journal Article › peer-review

18 Scopus citations

Abstract

A new chlorinated briarane-type diterpenoid, 12-epi-fragilide G (1), was isolated from the gorgonian coral Ellisella robusta. The structure of 1 was elucidated by the interpretations of spectral data analysis and this compound was found to possess an s-cis diene moiety in its structure. Briarane 1 displayed inhibitory effects on elastase release by human neutrophils.

Original language	English
Pages (from-to)	991-996
Number of pages	6
Journal	Heterocycles
Volume	81
Issue number	4
DOIs	https://doi.org/10.3987/COM-09-11899
State	Published - 01 04 2010

Keywords

Briarane
Diterpenoid
Ellisella robusta
Gorgonian
Robustolide

Access to Document

10.3987/COM-09-11899

Cite this

@article{b2b35fa8d1834128ac9196df01b939ac,

title = "12-epi-fragilide G, a new briarane-type diterpenoid from the gorgonian coral Ellisella robusta",

abstract = "A new chlorinated briarane-type diterpenoid, 12-epi-fragilide G (1), was isolated from the gorgonian coral Ellisella robusta. The structure of 1 was elucidated by the interpretations of spectral data analysis and this compound was found to possess an s-cis diene moiety in its structure. Briarane 1 displayed inhibitory effects on elastase release by human neutrophils.",

keywords = "Briarane, Diterpenoid, Ellisella robusta, Gorgonian, Robustolide",

author = "Chang, {Yu Chia} and Hwang, {Tsong Long} and Huang, {Sheng Kai} and Huang, {Li Wan} and Lin, {Mei Ru} and Sung, {Ping Jyun}",

year = "2010",

month = apr,

day = "1",

doi = "10.3987/COM-09-11899",

language = "英语",

volume = "81",

pages = "991--996",

journal = "Heterocycles",

issn = "0385-5414",

publisher = "Japan Institute of Heterocyclic Chemistry",

number = "4",

}

TY - JOUR

T1 - 12-epi-fragilide G, a new briarane-type diterpenoid from the gorgonian coral Ellisella robusta

AU - Chang, Yu Chia

AU - Hwang, Tsong Long

AU - Huang, Sheng Kai

AU - Huang, Li Wan

AU - Lin, Mei Ru

AU - Sung, Ping Jyun

PY - 2010/4/1

Y1 - 2010/4/1

N2 - A new chlorinated briarane-type diterpenoid, 12-epi-fragilide G (1), was isolated from the gorgonian coral Ellisella robusta. The structure of 1 was elucidated by the interpretations of spectral data analysis and this compound was found to possess an s-cis diene moiety in its structure. Briarane 1 displayed inhibitory effects on elastase release by human neutrophils.

AB - A new chlorinated briarane-type diterpenoid, 12-epi-fragilide G (1), was isolated from the gorgonian coral Ellisella robusta. The structure of 1 was elucidated by the interpretations of spectral data analysis and this compound was found to possess an s-cis diene moiety in its structure. Briarane 1 displayed inhibitory effects on elastase release by human neutrophils.

KW - Briarane

KW - Diterpenoid

KW - Ellisella robusta

KW - Gorgonian

KW - Robustolide

UR - http://www.scopus.com/inward/record.url?scp=77954291204&partnerID=8YFLogxK

U2 - 10.3987/COM-09-11899

DO - 10.3987/COM-09-11899

M3 - 文章

AN - SCOPUS:77954291204

SN - 0385-5414

VL - 81

SP - 991

EP - 996

JO - Heterocycles

JF - Heterocycles

IS - 4

ER -

12-epi-fragilide G, a new briarane-type diterpenoid from the gorgonian coral Ellisella robusta

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this