16-Hydroxybriaranes from the octocoral Briareum stechei

Chia Jung Liu; Chien Chiao Wang; Chun Feng Chang; Mingzi M. Zhang; Lun Kelvin Tsou; Zhi Hong Wen; Tsong Long Hwang; You Ying Chen; Ping Jyun Sung

doi:10.1016/j.phytol.2023.07.020

16-Hydroxybriaranes from the octocoral Briareum stechei

Chia Jung Liu
, Chien Chiao Wang
, Chun Feng Chang
, Mingzi M. Zhang
, Lun Kelvin Tsou
, Zhi Hong Wen
, Tsong Long Hwang^*
, You Ying Chen^*
, Ping Jyun Sung

^*Corresponding author for this work

School of Traditional Chinese Medicine

National Sun Yat-sen University
National Museum of Marine Biology and Aquarium, Taiwan
Chang Gung University
Kaohsiung Armed Forces General Hospital
National Health Research Institutes Taiwan
Chang Gung Memorial Hospital
Chang Gung University of Science and Technology
Ming Chi University of Technology
China Medical University Taichung
Kaohsiung Medical University
Fu Jen Catholic University

Research output: Contribution to journal › Journal Article › peer-review

3 Scopus citations

Abstract

Two new 16-hydroxybriaranes, 11-dehydroxybriavioid B (1) and 12-epi-briastecholide L (2), have been isolated from an algal-containing octocoral identified as Briareum stechei. The structures of metabolites 1 and 2 were corroborated by extensive 2D-NMR studies and comparison with literature data. Briarane 2 was found to reduce the release of inducible nitric oxide synthase (iNOS) to 87.92 %, at a concentration of 10 μM.

Original language	English
Pages (from-to)	92-95
Number of pages	4
Journal	Phytochemistry Letters
Volume	57
DOIs	https://doi.org/10.1016/j.phytol.2023.07.020
State	Published - 10 2023

Bibliographical note

Publisher Copyright:
© 2023 Phytochemical Society of Europe

Keywords

Briarane
Briareum stechei
Briastecholide
Briavioid
iNOS

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10.1016/j.phytol.2023.07.020

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title = "16-Hydroxybriaranes from the octocoral Briareum stechei",

abstract = "Two new 16-hydroxybriaranes, 11-dehydroxybriavioid B (1) and 12-epi-briastecholide L (2), have been isolated from an algal-containing octocoral identified as Briareum stechei. The structures of metabolites 1 and 2 were corroborated by extensive 2D-NMR studies and comparison with literature data. Briarane 2 was found to reduce the release of inducible nitric oxide synthase (iNOS) to 87.92 \%, at a concentration of 10 μM.",

keywords = "Briarane, Briareum stechei, Briastecholide, Briavioid, iNOS",

author = "Liu, \{Chia Jung\} and Wang, \{Chien Chiao\} and Chang, \{Chun Feng\} and Zhang, \{Mingzi M.\} and Tsou, \{Lun Kelvin\} and Wen, \{Zhi Hong\} and Hwang, \{Tsong Long\} and Chen, \{You Ying\} and Sung, \{Ping Jyun\}",

note = "Publisher Copyright: {\textcopyright} 2023 Phytochemical Society of Europe",

year = "2023",

month = oct,

doi = "10.1016/j.phytol.2023.07.020",

language = "英语",

volume = "57",

pages = "92--95",

journal = "Phytochemistry Letters",

issn = "1874-3900",

publisher = "Elsevier Ltd",

}

TY - JOUR

T1 - 16-Hydroxybriaranes from the octocoral Briareum stechei

AU - Liu, Chia Jung

AU - Wang, Chien Chiao

AU - Chang, Chun Feng

AU - Zhang, Mingzi M.

AU - Tsou, Lun Kelvin

AU - Wen, Zhi Hong

AU - Hwang, Tsong Long

AU - Chen, You Ying

AU - Sung, Ping Jyun

PY - 2023/10

Y1 - 2023/10

N2 - Two new 16-hydroxybriaranes, 11-dehydroxybriavioid B (1) and 12-epi-briastecholide L (2), have been isolated from an algal-containing octocoral identified as Briareum stechei. The structures of metabolites 1 and 2 were corroborated by extensive 2D-NMR studies and comparison with literature data. Briarane 2 was found to reduce the release of inducible nitric oxide synthase (iNOS) to 87.92 %, at a concentration of 10 μM.

AB - Two new 16-hydroxybriaranes, 11-dehydroxybriavioid B (1) and 12-epi-briastecholide L (2), have been isolated from an algal-containing octocoral identified as Briareum stechei. The structures of metabolites 1 and 2 were corroborated by extensive 2D-NMR studies and comparison with literature data. Briarane 2 was found to reduce the release of inducible nitric oxide synthase (iNOS) to 87.92 %, at a concentration of 10 μM.

KW - Briarane

KW - Briareum stechei

KW - Briastecholide

KW - Briavioid

KW - iNOS

UR - https://www.scopus.com/pages/publications/85166567349

U2 - 10.1016/j.phytol.2023.07.020

DO - 10.1016/j.phytol.2023.07.020

M3 - 文章

AN - SCOPUS:85166567349

SN - 1874-3900

VL - 57

SP - 92

EP - 95

JO - Phytochemistry Letters

JF - Phytochemistry Letters

ER -

16-Hydroxybriaranes from the octocoral Briareum stechei

Abstract

Bibliographical note

Keywords

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