A case of bilateral otomycosis associated with Aspergillus flavus and A. terreus in Taiwan

R. Kirschner*, P. L. Sun, S. L. Huang, C. L. Chen, C. P. Yang

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

5 Scopus citations


Otitis externa caused by fungi (otomycosis) occurs more commonly in tropical areas with high moisture than in temperate regions. Bilateral otomycosis is, however, rarely reported. In a case of bilateral otitis externa in a 56-year-old male patient in Taiwan, direct microscopic examination of the cerumen as well as isolation of strains indicated the presence of two Aspergillus species being different in each of both ears. The species were identified by DNA sequence comparisons and additional morphological confirmation of diagnostic characteristics as Aspergillus flavus and Aspergillus terreus. The rarely reported occurrence of two Aspergillus species in otitis of the same patient deserves attention in other cases of otomycosis, particularly with respect to potentially different resistances of different species against antifungals. Treatment with nystatin/neomycin was not successful, but with clotrimazole was effective.

Original languageEnglish
Pages (from-to)412-416
Number of pages5
JournalJournal de Mycologie Medicale
Issue number3
StatePublished - 09 2017

Bibliographical note

Publisher Copyright:
© 2017 Elsevier Masson SAS


  • Beta-tubulin gene
  • Eurotiales
  • Hyphomycetes
  • Internal transcribed spacer (ITS)
  • Molds


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