A combined micro-PET/CT scanner for small animal imaging

Meei Ling Jan; Yu Ching Ni; Kuo Wei Chen; Hsing Ching Liang; Keh Shih Chuang; Ying Kai Fu

doi:10.1016/j.nima.2006.08.106

A combined micro-PET/CT scanner for small animal imaging

Meei Ling Jan^*
, Yu Ching Ni
, Kuo Wei Chen
, Hsing Ching Liang
, Keh Shih Chuang
, Ying Kai Fu

^*Corresponding author for this work

Institute of Nuclear Energy Research Taiwan
National Tsing Hua University

Research output: Contribution to journal › Journal Article › peer-review

19 Scopus citations

Abstract

A micro-PET/CT system was developed by combination of an in-house micro-CT and a microPET^® R4 scanner. The cone-beam micro-CT consists of a rotational gantry that fits an X-ray tube, a CCD-based X-ray detector, and motor-driven linear stages. The gantry was designed to be coaxial with the scanner of microPET^® R4. It can be moved for the convenience of mounting the Ge-68 point-source holder for PET's calibration. The image volumes obtained from two modalities is registered by a pre-determined, inherent spatial transformation function. This hardware-approach fusion, which provides accurate and no labor-intensive alignment, is suitable for mass scanning. The micro-PET/CT system has been operated successfully. Merging the anatomical and functional images benefit studies of the small animal imaging.

Original language	English
Pages (from-to)	314-318
Number of pages	5
Journal	Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
Volume	569
Issue number	2 SPEC. ISS.
DOIs	https://doi.org/10.1016/j.nima.2006.08.106
State	Published - 20 12 2006
Externally published	Yes

Keywords

Fusion
Micro-CT
Micro-PET
Micro-PET/CT
Small animal imaging

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10.1016/j.nima.2006.08.106

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title = "A combined micro-PET/CT scanner for small animal imaging",

abstract = "A micro-PET/CT system was developed by combination of an in-house micro-CT and a microPET{\textregistered} R4 scanner. The cone-beam micro-CT consists of a rotational gantry that fits an X-ray tube, a CCD-based X-ray detector, and motor-driven linear stages. The gantry was designed to be coaxial with the scanner of microPET{\textregistered} R4. It can be moved for the convenience of mounting the Ge-68 point-source holder for PET's calibration. The image volumes obtained from two modalities is registered by a pre-determined, inherent spatial transformation function. This hardware-approach fusion, which provides accurate and no labor-intensive alignment, is suitable for mass scanning. The micro-PET/CT system has been operated successfully. Merging the anatomical and functional images benefit studies of the small animal imaging.",

keywords = "Fusion, Micro-CT, Micro-PET, Micro-PET/CT, Small animal imaging",

author = "Jan, \{Meei Ling\} and Ni, \{Yu Ching\} and Chen, \{Kuo Wei\} and Liang, \{Hsing Ching\} and Chuang, \{Keh Shih\} and Fu, \{Ying Kai\}",

year = "2006",

month = dec,

day = "20",

doi = "10.1016/j.nima.2006.08.106",

language = "英语",

volume = "569",

pages = "314--318",

journal = "Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment",

issn = "0168-9002",

publisher = "Elsevier B.V.",

number = "2 SPEC. ISS.",

}

A combined micro-PET/CT scanner for small animal imaging. / Jan, Meei Ling; Ni, Yu Ching; Chen, Kuo Wei et al.
In: Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Vol. 569, No. 2 SPEC. ISS., 20.12.2006, p. 314-318.

Research output: Contribution to journal › Journal Article › peer-review

TY - JOUR

T1 - A combined micro-PET/CT scanner for small animal imaging

AU - Jan, Meei Ling

AU - Ni, Yu Ching

AU - Chen, Kuo Wei

AU - Liang, Hsing Ching

AU - Chuang, Keh Shih

AU - Fu, Ying Kai

PY - 2006/12/20

Y1 - 2006/12/20

N2 - A micro-PET/CT system was developed by combination of an in-house micro-CT and a microPET® R4 scanner. The cone-beam micro-CT consists of a rotational gantry that fits an X-ray tube, a CCD-based X-ray detector, and motor-driven linear stages. The gantry was designed to be coaxial with the scanner of microPET® R4. It can be moved for the convenience of mounting the Ge-68 point-source holder for PET's calibration. The image volumes obtained from two modalities is registered by a pre-determined, inherent spatial transformation function. This hardware-approach fusion, which provides accurate and no labor-intensive alignment, is suitable for mass scanning. The micro-PET/CT system has been operated successfully. Merging the anatomical and functional images benefit studies of the small animal imaging.

AB - A micro-PET/CT system was developed by combination of an in-house micro-CT and a microPET® R4 scanner. The cone-beam micro-CT consists of a rotational gantry that fits an X-ray tube, a CCD-based X-ray detector, and motor-driven linear stages. The gantry was designed to be coaxial with the scanner of microPET® R4. It can be moved for the convenience of mounting the Ge-68 point-source holder for PET's calibration. The image volumes obtained from two modalities is registered by a pre-determined, inherent spatial transformation function. This hardware-approach fusion, which provides accurate and no labor-intensive alignment, is suitable for mass scanning. The micro-PET/CT system has been operated successfully. Merging the anatomical and functional images benefit studies of the small animal imaging.

KW - Fusion

KW - Micro-CT

KW - Micro-PET

KW - Micro-PET/CT

KW - Small animal imaging

UR - https://www.scopus.com/pages/publications/33751394298

U2 - 10.1016/j.nima.2006.08.106

DO - 10.1016/j.nima.2006.08.106

M3 - 文章

AN - SCOPUS:33751394298

SN - 0168-9002

VL - 569

SP - 314

EP - 318

JO - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

JF - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

IS - 2 SPEC. ISS.

ER -

A combined micro-PET/CT scanner for small animal imaging

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Keywords

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