A droplet-based microfluidic system capable of droplet formation and manipulation

Chen Yi Lee, Yen Heng Lin, Gwo Bin Lee*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

44 Scopus citations

Abstract

Formation of emulsion droplets is crucial for a variety of industrial and scientific applications. This study presents a new droplet-based microfluidic system capable of generating tunable and uniform-sized droplets and subsequently deflecting these droplets at various inclination angles using a combination of flow-focusing and moving-wall structures. A pneumatic air chamber was used to activate the moving-wall structures, located nearby the outlet of the flow-focusing microchannels, such that the sheath flows can be locally accelerated. With this approach, the size of the droplets can be fine-tuned and sorted without adjusting the syringe pumps. Experimental data showed that droplets with diameters ranging from 31.4 to 146.2 μm with a variation of less than 5.39% can be generated. Besides, droplets can be sorted upwards or backwards with an inclination angle ranging from 0° to 53.5°. The development of this emulsion system may be promising for the formation and collection of emulsion products for applications in the pharmaceutical, cosmetics and food industries.

Original languageEnglish
Pages (from-to)599-610
Number of pages12
JournalMicrofluidics and Nanofluidics
Volume6
Issue number5
DOIs
StatePublished - 05 2009
Externally publishedYes

Keywords

  • Emulsification
  • Flow focusing
  • MEMS
  • Microfluidics
  • Moving wall

Fingerprint

Dive into the research topics of 'A droplet-based microfluidic system capable of droplet formation and manipulation'. Together they form a unique fingerprint.

Cite this