A multifunctional embryos manipulative microfluidic chip with dynamic flow resistance trapping and CO-culture with stromal cells

Tzu Wei Lo; Yu Shih Chen; Ling Yi Ke; Ming Xiang Dong; Yao Shien Huang; Hong Yuan Huang; Cheng Hsien Liu

doi:10.1109/TRANSDUCERS.2017.7994107

A multifunctional embryos manipulative microfluidic chip with dynamic flow resistance trapping and CO-culture with stromal cells

Tzu Wei Lo^*, Yu Shih Chen, Ling Yi Ke, Ming Xiang Dong, Yao Shien Huang, Hong Yuan Huang, Cheng Hsien Liu

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

In order to optimize the quality of embryos culture, more factors are used to improve the quality of embryos. This microfluidic device integrates the various functions, such as the trapping mechanism of dynamic flow resistance, and co-culture embryos with human stromal cells providing the growth factors. For the main function, embryos can be manipulated by fluidic field in the G-type co-culture chamber (GCC), which can make the embryos grow better by keeping them moving when co-culturing. It's expected that the successful rate of embryos development and the quality can be improved by constructing the suitable environment to provide the physical stimulus for the embryos.

Original language	English
Title of host publication	TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	548-551
Number of pages	4
ISBN (Electronic)	9781538627310
DOIs	https://doi.org/10.1109/TRANSDUCERS.2017.7994107
State	Published - 26 07 2017
Externally published	Yes
Event	19th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2017 - Kaohsiung, Taiwan Duration: 18 06 2017 → 22 06 2017

Publication series

Name	TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems

Conference

Conference	19th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2017
Country/Territory	Taiwan
City	Kaohsiung
Period	18/06/17 → 22/06/17

Bibliographical note

Publisher Copyright:
© 2017 IEEE.

Keywords

Uterus-mimicking
co-culture
embryo manipulation
embryo trapping
stromal cells

Access to Document

10.1109/TRANSDUCERS.2017.7994107

Cite this

Lo, T. W., Chen, Y. S., Ke, L. Y., Dong, M. X., Huang, Y. S., Huang, H. Y., & Liu, C. H. (2017). A multifunctional embryos manipulative microfluidic chip with dynamic flow resistance trapping and CO-culture with stromal cells. In TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems (pp. 548-551). Article 7994107 (TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/TRANSDUCERS.2017.7994107

Lo, Tzu Wei ; Chen, Yu Shih ; Ke, Ling Yi et al. / A multifunctional embryos manipulative microfluidic chip with dynamic flow resistance trapping and CO-culture with stromal cells. TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems. Institute of Electrical and Electronics Engineers Inc., 2017. pp. 548-551 (TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems).

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title = "A multifunctional embryos manipulative microfluidic chip with dynamic flow resistance trapping and CO-culture with stromal cells",

abstract = "In order to optimize the quality of embryos culture, more factors are used to improve the quality of embryos. This microfluidic device integrates the various functions, such as the trapping mechanism of dynamic flow resistance, and co-culture embryos with human stromal cells providing the growth factors. For the main function, embryos can be manipulated by fluidic field in the G-type co-culture chamber (GCC), which can make the embryos grow better by keeping them moving when co-culturing. It's expected that the successful rate of embryos development and the quality can be improved by constructing the suitable environment to provide the physical stimulus for the embryos.",

keywords = "Uterus-mimicking, co-culture, embryo manipulation, embryo trapping, stromal cells",

author = "Lo, {Tzu Wei} and Chen, {Yu Shih} and Ke, {Ling Yi} and Dong, {Ming Xiang} and Huang, {Yao Shien} and Huang, {Hong Yuan} and Liu, {Cheng Hsien}",

note = "Publisher Copyright: {\textcopyright} 2017 IEEE.; 19th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2017 ; Conference date: 18-06-2017 Through 22-06-2017",

year = "2017",

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day = "26",

doi = "10.1109/TRANSDUCERS.2017.7994107",

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series = "TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems",

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Lo, TW, Chen, YS, Ke, LY, Dong, MX, Huang, YS, Huang, HY & Liu, CH 2017, A multifunctional embryos manipulative microfluidic chip with dynamic flow resistance trapping and CO-culture with stromal cells. in TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems., 7994107, TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems, Institute of Electrical and Electronics Engineers Inc., pp. 548-551, 19th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2017, Kaohsiung, Taiwan, 18/06/17. https://doi.org/10.1109/TRANSDUCERS.2017.7994107

A multifunctional embryos manipulative microfluidic chip with dynamic flow resistance trapping and CO-culture with stromal cells. / Lo, Tzu Wei; Chen, Yu Shih; Ke, Ling Yi et al.
TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems. Institute of Electrical and Electronics Engineers Inc., 2017. p. 548-551 7994107 (TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - A multifunctional embryos manipulative microfluidic chip with dynamic flow resistance trapping and CO-culture with stromal cells

AU - Lo, Tzu Wei

AU - Chen, Yu Shih

AU - Ke, Ling Yi

AU - Dong, Ming Xiang

AU - Huang, Yao Shien

AU - Huang, Hong Yuan

AU - Liu, Cheng Hsien

PY - 2017/7/26

Y1 - 2017/7/26

N2 - In order to optimize the quality of embryos culture, more factors are used to improve the quality of embryos. This microfluidic device integrates the various functions, such as the trapping mechanism of dynamic flow resistance, and co-culture embryos with human stromal cells providing the growth factors. For the main function, embryos can be manipulated by fluidic field in the G-type co-culture chamber (GCC), which can make the embryos grow better by keeping them moving when co-culturing. It's expected that the successful rate of embryos development and the quality can be improved by constructing the suitable environment to provide the physical stimulus for the embryos.

AB - In order to optimize the quality of embryos culture, more factors are used to improve the quality of embryos. This microfluidic device integrates the various functions, such as the trapping mechanism of dynamic flow resistance, and co-culture embryos with human stromal cells providing the growth factors. For the main function, embryos can be manipulated by fluidic field in the G-type co-culture chamber (GCC), which can make the embryos grow better by keeping them moving when co-culturing. It's expected that the successful rate of embryos development and the quality can be improved by constructing the suitable environment to provide the physical stimulus for the embryos.

KW - Uterus-mimicking

KW - co-culture

KW - embryo manipulation

KW - embryo trapping

KW - stromal cells

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AN - SCOPUS:85029385976

T3 - TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems

SP - 548

EP - 551

BT - TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2017

Y2 - 18 June 2017 through 22 June 2017

ER -

Lo TW, Chen YS, Ke LY, Dong MX, Huang YS, Huang HY et al. A multifunctional embryos manipulative microfluidic chip with dynamic flow resistance trapping and CO-culture with stromal cells. In TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems. Institute of Electrical and Electronics Engineers Inc. 2017. p. 548-551. 7994107. (TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems). doi: 10.1109/TRANSDUCERS.2017.7994107

A multifunctional embryos manipulative microfluidic chip with dynamic flow resistance trapping and CO-culture with stromal cells

Abstract

Publication series

Conference

Bibliographical note

Keywords

Access to Document

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