A new hydroxychavicol dimer from the roots of Piper betle

Chwan Fwu Lin; Tsong Long Hwang; Chun Chien Chien; Huei Yu Tu; Horng Liang Lay

doi:10.3390/molecules18032563

A new hydroxychavicol dimer from the roots of Piper betle

Chwan Fwu Lin, Tsong Long Hwang, Chun Chien Chien, Huei Yu Tu, Horng Liang Lay^*

^*Corresponding author for this work

School of Traditional Chinese Medicine

Research output: Contribution to journal › Journal Article › peer-review

41 Scopus citations

Abstract

A new hydroxychavicol dimer, 2-(γ'-hydroxychavicol)-hydroxychavicol (1), was isolated from the roots of Piper betle Linn. along with five known compounds, hydroxychavicol (2), aristololactam A II (3), aristololactam B II (4), piperolactam A (5) and cepharadione A (6). The structures of these isolated compounds were elucidated by spectroscopic methods. Compounds 1 and 2 exhibited inhibitory effects on the generation of superoxide anion and the release of elastase by human neutrophils.

Original language	English
Pages (from-to)	2563-2570
Number of pages	8
Journal	Molecules
Volume	18
Issue number	3
DOIs	https://doi.org/10.3390/molecules18032563
State	Published - 03 2013

Keywords

2-(γ'-hydroxychavicol)-hydroxychavicol
Elastase
Hydroxychavciol
Neutrophils
Piper betle
Superoxide anion

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10.3390/molecules18032563

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title = "A new hydroxychavicol dimer from the roots of Piper betle",

abstract = "A new hydroxychavicol dimer, 2-(γ'-hydroxychavicol)-hydroxychavicol (1), was isolated from the roots of Piper betle Linn. along with five known compounds, hydroxychavicol (2), aristololactam A II (3), aristololactam B II (4), piperolactam A (5) and cepharadione A (6). The structures of these isolated compounds were elucidated by spectroscopic methods. Compounds 1 and 2 exhibited inhibitory effects on the generation of superoxide anion and the release of elastase by human neutrophils.",

keywords = "2-(γ'-hydroxychavicol)-hydroxychavicol, Elastase, Hydroxychavciol, Neutrophils, Piper betle, Superoxide anion",

author = "Lin, {Chwan Fwu} and Hwang, {Tsong Long} and Chien, {Chun Chien} and Tu, {Huei Yu} and Lay, {Horng Liang}",

year = "2013",

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T1 - A new hydroxychavicol dimer from the roots of Piper betle

AU - Lin, Chwan Fwu

AU - Hwang, Tsong Long

AU - Chien, Chun Chien

AU - Tu, Huei Yu

AU - Lay, Horng Liang

PY - 2013/3

Y1 - 2013/3

N2 - A new hydroxychavicol dimer, 2-(γ'-hydroxychavicol)-hydroxychavicol (1), was isolated from the roots of Piper betle Linn. along with five known compounds, hydroxychavicol (2), aristololactam A II (3), aristololactam B II (4), piperolactam A (5) and cepharadione A (6). The structures of these isolated compounds were elucidated by spectroscopic methods. Compounds 1 and 2 exhibited inhibitory effects on the generation of superoxide anion and the release of elastase by human neutrophils.

AB - A new hydroxychavicol dimer, 2-(γ'-hydroxychavicol)-hydroxychavicol (1), was isolated from the roots of Piper betle Linn. along with five known compounds, hydroxychavicol (2), aristololactam A II (3), aristololactam B II (4), piperolactam A (5) and cepharadione A (6). The structures of these isolated compounds were elucidated by spectroscopic methods. Compounds 1 and 2 exhibited inhibitory effects on the generation of superoxide anion and the release of elastase by human neutrophils.

KW - 2-(γ'-hydroxychavicol)-hydroxychavicol

KW - Elastase

KW - Hydroxychavciol

KW - Neutrophils

KW - Piper betle

KW - Superoxide anion

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DO - 10.3390/molecules18032563

M3 - 文章

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AN - SCOPUS:84875631653

SN - 1420-3049

VL - 18

SP - 2563

EP - 2570

JO - Molecules

JF - Molecules

IS - 3

ER -

A new hydroxychavicol dimer from the roots of Piper betle

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Keywords

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