A novel cell irradiation system using 90°-scattering technique

I. C. Cho; M. F. Weng; J. M. Wu; S. Y. Chiang; W. T. Chou; H. Niu; C. H. Hsu

doi:10.1109/tns.2010.2087036

A novel cell irradiation system using 90°-scattering technique

I. C. Cho
, M. F. Weng
, J. M. Wu
, S. Y. Chiang
, W. T. Chou
, H. Niu
, C. H. Hsu

Department of Biological Engineering and Environmental Sciences
National Tsing Hua University
National Synchrotron Radiation Research Center Taiwan
National Yang Ming Chiao Tung University
Department of Radiation Oncology
I-Shou University
Department of Medical Imagines and Radiological Science

Research output: Contribution to journal › Journal Article › peer-review

4 Scopus citations

Abstract

A novel cell irradiation system was developed for use with the HVEE Van de Graaff accelerator at the National Tsing Hua University. A 90°-scattering technique using an Au foil was designed, in which charged particles were directed from horizontal to vertical irradiation. Beam performance was tested with a silicon detector and a CR-39 nuclear track detector. The HeLa cells were irradiated with 2-MeV alpha particles and the formation of giant cells was observed. The result showed that this system provides a convenient way of generating a vertical particle beam and a cell-supporting chamber, thereby allowing a suitable cell growth condition during irradiation. Furthermore, establishment of such a system is more convenient and economical than the alternatives.

Original language	English
Article number	5618602
Pages (from-to)	95-98
Number of pages	4
Journal	IEEE Transactions on Nuclear Science
Volume	58
Issue number	1 PART 1
DOIs	https://doi.org/10.1109/tns.2010.2087036 https://doi.org/10.1109/TNS.2010.2087036
State	Published - 02 2011
Externally published	Yes

Keywords

Accelerator
biological effect of radiation
ion beam applications

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title = "A novel cell irradiation system using 90°-scattering technique",

abstract = "A novel cell irradiation system was developed for use with the HVEE Van de Graaff accelerator at the National Tsing Hua University. A 90°-scattering technique using an Au foil was designed, in which charged particles were directed from horizontal to vertical irradiation. Beam performance was tested with a silicon detector and a CR-39 nuclear track detector. The HeLa cells were irradiated with 2-MeV alpha particles and the formation of giant cells was observed. The result showed that this system provides a convenient way of generating a vertical particle beam and a cell-supporting chamber, thereby allowing a suitable cell growth condition during irradiation. Furthermore, establishment of such a system is more convenient and economical than the alternatives.",

keywords = "Accelerator, biological effect of radiation, ion beam applications",

author = "Cho, \{I. C.\} and Weng, \{M. F.\} and Wu, \{J. M.\} and Chiang, \{S. Y.\} and Chou, \{W. T.\} and H. Niu and Hsu, \{C. H.\}",

year = "2011",

month = feb,

doi = "10.1109/tns.2010.2087036",

language = "英语",

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TY - JOUR

T1 - A novel cell irradiation system using 90°-scattering technique

AU - Cho, I. C.

AU - Weng, M. F.

AU - Wu, J. M.

AU - Chiang, S. Y.

AU - Chou, W. T.

AU - Niu, H.

AU - Hsu, C. H.

PY - 2011/2

Y1 - 2011/2

N2 - A novel cell irradiation system was developed for use with the HVEE Van de Graaff accelerator at the National Tsing Hua University. A 90°-scattering technique using an Au foil was designed, in which charged particles were directed from horizontal to vertical irradiation. Beam performance was tested with a silicon detector and a CR-39 nuclear track detector. The HeLa cells were irradiated with 2-MeV alpha particles and the formation of giant cells was observed. The result showed that this system provides a convenient way of generating a vertical particle beam and a cell-supporting chamber, thereby allowing a suitable cell growth condition during irradiation. Furthermore, establishment of such a system is more convenient and economical than the alternatives.

AB - A novel cell irradiation system was developed for use with the HVEE Van de Graaff accelerator at the National Tsing Hua University. A 90°-scattering technique using an Au foil was designed, in which charged particles were directed from horizontal to vertical irradiation. Beam performance was tested with a silicon detector and a CR-39 nuclear track detector. The HeLa cells were irradiated with 2-MeV alpha particles and the formation of giant cells was observed. The result showed that this system provides a convenient way of generating a vertical particle beam and a cell-supporting chamber, thereby allowing a suitable cell growth condition during irradiation. Furthermore, establishment of such a system is more convenient and economical than the alternatives.

KW - Accelerator

KW - biological effect of radiation

KW - ion beam applications

UR - https://www.scopus.com/pages/publications/79951672426

U2 - 10.1109/tns.2010.2087036

DO - 10.1109/tns.2010.2087036

M3 - 文章

SN - 0018-9499

VL - 58

SP - 95

EP - 98

JO - IEEE Transactions on Nuclear Science

JF - IEEE Transactions on Nuclear Science

IS - 1 PART 1

M1 - 5618602

ER -

A novel cell irradiation system using 90°-scattering technique

Abstract

Keywords

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