A physical map of 30,000 human genes

P. Deloukas; G. D. Schuler; G. Gyapay; E. M. Beasley; C. Soderlund; P. Rodriguez-Tomé; L. Hui; T. C. Matise; K. B. McKusick; J. S. Beckmann; S. Bentolila; M. T. Bihoreau; B. B. Birren; J. Browne; A. Butler; A. B. Castle; N. Chiannilkulchai; C. Clee; P. J.R. Day; A. Dehejia; T. Dibling; N. Drouot; S. Duprat; C. Fizames; S. Fox; S. Gelling; L. Green; P. Harrison; R. Hocking; E. Holloway; S. Hunt; S. Keil; P. Lijnzaad; C. Louis-Dit-Sully; J. Ma; A. Mendis; J. Miller; J. Morissette; D. Muselet; H. C. Nusbaum; A. Peck; S. Rozen; D. Simon; D. K. Slonim; R. Staples; L. D. Stein; E. A. Stewart; M. A. Suchard; T. Thangarajah; N. Vega-Czarny; C. Webber; X. Wu; J. Hudson; C. Auffray; N. Nomura; J. M. Sikela; M. H. Polymeropoulos; M. R. James; E. S. Lander; T. J. Hudson; R. M. Myers; D. R. Cox; J. Weissenbach; M. S. Boguski; D. R. Bentley

doi:10.1126/science.282.5389.744

A physical map of 30,000 human genes

P. Deloukas^*, G. D. Schuler, G. Gyapay, E. M. Beasley, C. Soderlund, P. Rodriguez-Tomé, L. Hui, T. C. Matise, K. B. McKusick, J. S. Beckmann, S. Bentolila, M. T. Bihoreau, B. B. Birren, J. Browne, A. Butler, A. B. Castle, N. Chiannilkulchai, C. Clee, P. J.R. Day, A. DehejiaT. Dibling, N. Drouot, S. Duprat, C. Fizames, S. Fox, S. Gelling, L. Green, P. Harrison, R. Hocking, E. Holloway, S. Hunt, S. Keil, P. Lijnzaad, C. Louis-Dit-Sully, J. Ma, A. Mendis, J. Miller, J. Morissette, D. Muselet, H. C. Nusbaum, A. Peck, S. Rozen, D. Simon, D. K. Slonim, R. Staples, L. D. Stein, E. A. Stewart, M. A. Suchard, T. Thangarajah, N. Vega-Czarny, C. Webber, X. Wu, J. Hudson, C. Auffray, N. Nomura, J. M. Sikela, M. H. Polymeropoulos, M. R. James, E. S. Lander, T. J. Hudson, R. M. Myers, D. R. Cox, J. Weissenbach, M. S. Boguski, D. R. Bentley

^*Corresponding author for this work

Graduate Institute of Biomedical Sciences

Research output: Contribution to journal › Journal Article › peer-review

603 Scopus citations

Abstract

A map of 30,181 human gene-based markers was assembled and integrated with the current genetic map by radiation hybrid mapping. The gene map contains nearly twice as many genes as the previous release, includes most genes that encode proteins of known function, and is twofold to threefold more accurate than the previous version. A redesigned, more informative and functional World Wide Web site (www.ncbi.nlm.nih.gov/genemap) provides the mapping information and associated data and annotations. This resource constitutes an important infrastructure and tool for the study of complex genetic traits, the positional cloning of disease genes, the cross- referencing of mammalian genomes, and validated human transcribed sequences for large-scale studies of gene expression.

Original language	English
Pages (from-to)	744-746
Number of pages	3
Journal	Science
Volume	282
Issue number	5389
DOIs	https://doi.org/10.1126/science.282.5389.744
State	Published - 23 10 1998

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Deloukas, P., Schuler, G. D., Gyapay, G., Beasley, E. M., Soderlund, C., Rodriguez-Tomé, P., Hui, L., Matise, T. C., McKusick, K. B., Beckmann, J. S., Bentolila, S., Bihoreau, M. T., Birren, B. B., Browne, J., Butler, A., Castle, A. B., Chiannilkulchai, N., Clee, C., Day, P. J. R., ... Bentley, D. R. (1998). A physical map of 30,000 human genes. Science, 282(5389), 744-746. https://doi.org/10.1126/science.282.5389.744

@article{f107d3766b854bbea108de35ecce19b7,

title = "A physical map of 30,000 human genes",

abstract = "A map of 30,181 human gene-based markers was assembled and integrated with the current genetic map by radiation hybrid mapping. The gene map contains nearly twice as many genes as the previous release, includes most genes that encode proteins of known function, and is twofold to threefold more accurate than the previous version. A redesigned, more informative and functional World Wide Web site (www.ncbi.nlm.nih.gov/genemap) provides the mapping information and associated data and annotations. This resource constitutes an important infrastructure and tool for the study of complex genetic traits, the positional cloning of disease genes, the cross- referencing of mammalian genomes, and validated human transcribed sequences for large-scale studies of gene expression.",

author = "P. Deloukas and Schuler, \{G. D.\} and G. Gyapay and Beasley, \{E. M.\} and C. Soderlund and P. Rodriguez-Tom{\'e} and L. Hui and Matise, \{T. C.\} and McKusick, \{K. B.\} and Beckmann, \{J. S.\} and S. Bentolila and Bihoreau, \{M. T.\} and Birren, \{B. B.\} and J. Browne and A. Butler and Castle, \{A. B.\} and N. Chiannilkulchai and C. Clee and Day, \{P. J.R.\} and A. Dehejia and T. Dibling and N. Drouot and S. Duprat and C. Fizames and S. Fox and S. Gelling and L. Green and P. Harrison and R. Hocking and E. Holloway and S. Hunt and S. Keil and P. Lijnzaad and C. Louis-Dit-Sully and J. Ma and A. Mendis and J. Miller and J. Morissette and D. Muselet and Nusbaum, \{H. C.\} and A. Peck and S. Rozen and D. Simon and Slonim, \{D. K.\} and R. Staples and Stein, \{L. D.\} and Stewart, \{E. A.\} and Suchard, \{M. A.\} and T. Thangarajah and N. Vega-Czarny and C. Webber and X. Wu and J. Hudson and C. Auffray and N. Nomura and Sikela, \{J. M.\} and Polymeropoulos, \{M. H.\} and James, \{M. R.\} and Lander, \{E. S.\} and Hudson, \{T. J.\} and Myers, \{R. M.\} and Cox, \{D. R.\} and J. Weissenbach and Boguski, \{M. S.\} and Bentley, \{D. R.\}",

year = "1998",

month = oct,

day = "23",

doi = "10.1126/science.282.5389.744",

language = "英语",

volume = "282",

pages = "744--746",

journal = "Science",

issn = "0036-8075",

publisher = "American Association for the Advancement of Science",

number = "5389",

}

Deloukas, P, Schuler, GD, Gyapay, G, Beasley, EM, Soderlund, C, Rodriguez-Tomé, P, Hui, L, Matise, TC, McKusick, KB, Beckmann, JS, Bentolila, S, Bihoreau, MT, Birren, BB, Browne, J, Butler, A, Castle, AB, Chiannilkulchai, N, Clee, C, Day, PJR, Dehejia, A, Dibling, T, Drouot, N, Duprat, S, Fizames, C, Fox, S, Gelling, S, Green, L, Harrison, P, Hocking, R, Holloway, E, Hunt, S, Keil, S, Lijnzaad, P, Louis-Dit-Sully, C, Ma, J, Mendis, A, Miller, J, Morissette, J, Muselet, D, Nusbaum, HC, Peck, A, Rozen, S, Simon, D, Slonim, DK, Staples, R, Stein, LD, Stewart, EA, Suchard, MA, Thangarajah, T, Vega-Czarny, N, Webber, C, Wu, X, Hudson, J, Auffray, C, Nomura, N, Sikela, JM, Polymeropoulos, MH, James, MR, Lander, ES, Hudson, TJ, Myers, RM, Cox, DR, Weissenbach, J, Boguski, MS & Bentley, DR 1998, 'A physical map of 30,000 human genes', Science, vol. 282, no. 5389, pp. 744-746. https://doi.org/10.1126/science.282.5389.744

TY - JOUR

T1 - A physical map of 30,000 human genes

AU - Deloukas, P.

AU - Schuler, G. D.

AU - Gyapay, G.

AU - Beasley, E. M.

AU - Soderlund, C.

AU - Rodriguez-Tomé, P.

AU - Hui, L.

AU - Matise, T. C.

AU - McKusick, K. B.

AU - Beckmann, J. S.

AU - Bentolila, S.

AU - Bihoreau, M. T.

AU - Birren, B. B.

AU - Browne, J.

AU - Butler, A.

AU - Castle, A. B.

AU - Chiannilkulchai, N.

AU - Clee, C.

AU - Day, P. J.R.

AU - Dehejia, A.

AU - Dibling, T.

AU - Drouot, N.

AU - Duprat, S.

AU - Fizames, C.

AU - Fox, S.

AU - Gelling, S.

AU - Green, L.

AU - Harrison, P.

AU - Hocking, R.

AU - Holloway, E.

AU - Hunt, S.

AU - Keil, S.

AU - Lijnzaad, P.

AU - Louis-Dit-Sully, C.

AU - Ma, J.

AU - Mendis, A.

AU - Miller, J.

AU - Morissette, J.

AU - Muselet, D.

AU - Nusbaum, H. C.

AU - Peck, A.

AU - Rozen, S.

AU - Simon, D.

AU - Slonim, D. K.

AU - Staples, R.

AU - Stein, L. D.

AU - Stewart, E. A.

AU - Suchard, M. A.

AU - Thangarajah, T.

AU - Vega-Czarny, N.

AU - Webber, C.

AU - Wu, X.

AU - Hudson, J.

AU - Auffray, C.

AU - Nomura, N.

AU - Sikela, J. M.

AU - Polymeropoulos, M. H.

AU - James, M. R.

AU - Lander, E. S.

AU - Hudson, T. J.

AU - Myers, R. M.

AU - Cox, D. R.

AU - Weissenbach, J.

AU - Boguski, M. S.

AU - Bentley, D. R.

PY - 1998/10/23

Y1 - 1998/10/23

N2 - A map of 30,181 human gene-based markers was assembled and integrated with the current genetic map by radiation hybrid mapping. The gene map contains nearly twice as many genes as the previous release, includes most genes that encode proteins of known function, and is twofold to threefold more accurate than the previous version. A redesigned, more informative and functional World Wide Web site (www.ncbi.nlm.nih.gov/genemap) provides the mapping information and associated data and annotations. This resource constitutes an important infrastructure and tool for the study of complex genetic traits, the positional cloning of disease genes, the cross- referencing of mammalian genomes, and validated human transcribed sequences for large-scale studies of gene expression.

AB - A map of 30,181 human gene-based markers was assembled and integrated with the current genetic map by radiation hybrid mapping. The gene map contains nearly twice as many genes as the previous release, includes most genes that encode proteins of known function, and is twofold to threefold more accurate than the previous version. A redesigned, more informative and functional World Wide Web site (www.ncbi.nlm.nih.gov/genemap) provides the mapping information and associated data and annotations. This resource constitutes an important infrastructure and tool for the study of complex genetic traits, the positional cloning of disease genes, the cross- referencing of mammalian genomes, and validated human transcribed sequences for large-scale studies of gene expression.

UR - https://www.scopus.com/pages/publications/0032561502

U2 - 10.1126/science.282.5389.744

DO - 10.1126/science.282.5389.744

M3 - 文章

C2 - 9784132

AN - SCOPUS:0032561502

SN - 0036-8075

VL - 282

SP - 744

EP - 746

JO - Science

JF - Science

IS - 5389

ER -

A physical map of 30,000 human genes

Abstract

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