A review on microfluidics: An aid to assisted reproductive technology

  • Anand Baby Alias
  • , Hong Yuan Huang*
  • , Da Jeng Yao*
  • *Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

32 Scopus citations

Abstract

Infertility is a state of the male or female reproductive system that is defined as the failure to achieve pregnancy even after 12 or more months of regular unprotected sexual intercourse. Assisted reproductive technology (ART) plays a crucial role in addressing infertility. Various ART are now available for infertile couples. Fertilization in vitro (IVF), intracytoplasmic sperm injection (ICSI) and intrauterine insemination (IUI) are the most common techniques in this regard. Various microfluidic technologies can incorporate various ART procedures such as embryo and gamete (sperm and oocyte) analysis, sorting, manipulation, culture and monitoring. Hence, this review intends to summarize the current knowledge about the application of this approach towards cell biology to enhance ART.

Original languageEnglish
Article number4354
JournalMolecules
Volume26
Issue number14
DOIs
StatePublished - 02 07 2021

Bibliographical note

Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.

Keywords

  • Assisted reproductive technology
  • Droplet microfluidics
  • Embryo culture
  • Fertilization in vitro
  • Sperm and oocyte

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