A row-action image reconstruction of short time frame for microPET dynamic study

A. Vasko*, C. H. Hsu, M. C. Lin, I. T. Hsiao, C. Wieholt, C. T. Chen

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Dynamic PET imaging usually involves the collection of a series of frames of sinogram data over contiguous short-time intervals. Since scans with shorter acquisition time are usually very noisy, iterative image reconstruction can not ensure for both stable and fast convergence. The more recently row-action maximum-likelihood algorithm (RAMLA) allows sequences of orthogonal projections and a relaxation parameter to control updating of the log-likelihood objective for sure convergence. For noisy and low-count sinogram, larger subset sizes with appropriate choice of relaxation scheme can be combined to achieve fast convergence. In this work, we investigate RAMLA with fixed relaxation parameter and with subset-dependent relaxation parameter of Tanaka and Kudo for microPET dynamic scans. The experimental results have indicated the RAMLA with subset-dependent relaxation parameter can reach the plateau of the likelihood function faster than RMLA with fixed relaxation. The OSEM algorithm with the same subset size fails to converge for such a low-count case. The smaller subset of OSEM is used, but the likelihood function converges to a sub-optimal solution. The results suggest that the RAMLA with subset-dependent relaxation scheme is suitable for low-count dynamic PET imaging using microPET.

Original languageEnglish
Title of host publication2005 IEEE Nuclear Science Symposium Conference Record -Nuclear Science Symposium and Medical Imaging Conference
Pages2510-2513
Number of pages4
DOIs
StatePublished - 2005
EventNuclear Science Symposium Conference Record, 2005 IEEE - , Puerto Rico
Duration: 23 10 200529 10 2005

Publication series

NameIEEE Nuclear Science Symposium Conference Record
Volume5
ISSN (Print)1095-7863

Conference

ConferenceNuclear Science Symposium Conference Record, 2005 IEEE
Country/TerritoryPuerto Rico
Period23/10/0529/10/05

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