A single dose of nebulized budesonide decreases exhaled nitric oxide in children with acute asthma

  • Yi Giien Tsai
  • , Ming Yung Lee
  • , Kuender D. Yang
  • , Der Ming Chu
  • , Yeong Seng Yuh
  • , Chih Hsing Hung*
  • *Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

61 Scopus citations

Abstract

This study was conducted to investigate whether a single dose of nebulized budesonide effectively decreased airway inflammation as demonstrated by exhaled nitric oxide (eNO) levels. A single dose of nebulized budesonide, but not nebulized terbutaline, rapidly decreased eNO levels in 6 hours. The decrease in eNO levels induced by nebulized budesonide was correlated to an increase in peak expiratory flow rate.

Original languageEnglish
Pages (from-to)433-437
Number of pages5
JournalJournal of Pediatrics
Volume139
Issue number3
DOIs
StatePublished - 2001

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