A systematic analysis of average molecular weights and gelation conditions for branched immune complexes: The interaction between a multivalent antigen with distinct epitopes and many different types of bivalent antibodies

Lie Ding Shiau*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

6 Scopus citations

Abstract

systematic model, based on standard equilibrium expressions and probability theory, is presented to calculate average molecular weights and gelation conditions for the immune system consisting of a single type of antigens with three (or more) different epitopes and three (or more) types of bivalent antibodies. Molecular weights M̄n, M̄w, M̄z, and any other higher average molecular weights of formed branched antigen-antibody complexes in such an immune system are calculated directly without determining the whole distribution. The conditions for the formation of gel complexes also can be determined by this model.

Original languageEnglish
Pages (from-to)445-454
Number of pages10
JournalBiopolymers - Peptide Science Section
Volume39
Issue number3
DOIs
StatePublished - 1996

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