A Turbidity Test Based Centrifugal Microfluidics Diagnostic System for Simultaneous Detection of HBV, HCV, and CMV

Hung Cheng Chang; Yu Tin Chao; Jia Yush Yen; Ya Lin Yu; Chun Nan Lee; Bing Ching Ho; Kou Chen Liu; Jiunn Fang; Chii Wann Lin; Jiun Haw Lee

doi:10.1155/2015/306708

A Turbidity Test Based Centrifugal Microfluidics Diagnostic System for Simultaneous Detection of HBV, HCV, and CMV

Hung Cheng Chang, Yu Tin Chao, Jia Yush Yen^*, Ya Lin Yu, Chun Nan Lee, Bing Ching Ho, Kou Chen Liu, Jiunn Fang, Chii Wann Lin, Jiun Haw Lee

^*Corresponding author for this work

Department of Electronic Engineering

Research output: Contribution to journal › Journal Article › peer-review

8 Scopus citations

Abstract

This paper presents a LAMP- (loop-mediated isothermal amplification-) based lab-on-disk optical system that allows the simultaneous detection of hepatitis B virus, hepatitis C virus, and cytomegalovirus. The various flow stages are controlled in the proposed system using different balance among centrifugal pumping, Coriolis pumping, and the capillary force. We have implemented a servo system for positioning and speed control for the heating and centrifugal pumping. We have also successfully employed a polymer light-emitting diode section for turbidity detection. The easy-to-use one-click system can perform diagnostics in less than 1 hour.

Original language	English
Article number	306708
Journal	Advances in Materials Science and Engineering
Volume	2015
DOIs	https://doi.org/10.1155/2015/306708
State	Published - 2015

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Publisher Copyright:
Copyright © 2015 Hung-Cheng Chang et al.

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title = "A Turbidity Test Based Centrifugal Microfluidics Diagnostic System for Simultaneous Detection of HBV, HCV, and CMV",

abstract = "This paper presents a LAMP- (loop-mediated isothermal amplification-) based lab-on-disk optical system that allows the simultaneous detection of hepatitis B virus, hepatitis C virus, and cytomegalovirus. The various flow stages are controlled in the proposed system using different balance among centrifugal pumping, Coriolis pumping, and the capillary force. We have implemented a servo system for positioning and speed control for the heating and centrifugal pumping. We have also successfully employed a polymer light-emitting diode section for turbidity detection. The easy-to-use one-click system can perform diagnostics in less than 1 hour.",

author = "Chang, {Hung Cheng} and Chao, {Yu Tin} and Yen, {Jia Yush} and Yu, {Ya Lin} and Lee, {Chun Nan} and Ho, {Bing Ching} and Liu, {Kou Chen} and Jiunn Fang and Lin, {Chii Wann} and Lee, {Jiun Haw}",

note = "Publisher Copyright: Copyright {\textcopyright} 2015 Hung-Cheng Chang et al.",

year = "2015",

doi = "10.1155/2015/306708",

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volume = "2015",

journal = "Advances in Materials Science and Engineering",

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T1 - A Turbidity Test Based Centrifugal Microfluidics Diagnostic System for Simultaneous Detection of HBV, HCV, and CMV

AU - Chang, Hung Cheng

AU - Chao, Yu Tin

AU - Yen, Jia Yush

AU - Yu, Ya Lin

AU - Lee, Chun Nan

AU - Ho, Bing Ching

AU - Liu, Kou Chen

AU - Fang, Jiunn

AU - Lin, Chii Wann

AU - Lee, Jiun Haw

PY - 2015

Y1 - 2015

N2 - This paper presents a LAMP- (loop-mediated isothermal amplification-) based lab-on-disk optical system that allows the simultaneous detection of hepatitis B virus, hepatitis C virus, and cytomegalovirus. The various flow stages are controlled in the proposed system using different balance among centrifugal pumping, Coriolis pumping, and the capillary force. We have implemented a servo system for positioning and speed control for the heating and centrifugal pumping. We have also successfully employed a polymer light-emitting diode section for turbidity detection. The easy-to-use one-click system can perform diagnostics in less than 1 hour.

AB - This paper presents a LAMP- (loop-mediated isothermal amplification-) based lab-on-disk optical system that allows the simultaneous detection of hepatitis B virus, hepatitis C virus, and cytomegalovirus. The various flow stages are controlled in the proposed system using different balance among centrifugal pumping, Coriolis pumping, and the capillary force. We have implemented a servo system for positioning and speed control for the heating and centrifugal pumping. We have also successfully employed a polymer light-emitting diode section for turbidity detection. The easy-to-use one-click system can perform diagnostics in less than 1 hour.

UR - http://www.scopus.com/inward/record.url?scp=84937685565&partnerID=8YFLogxK

U2 - 10.1155/2015/306708

DO - 10.1155/2015/306708

M3 - 文章

AN - SCOPUS:84937685565

SN - 1687-8434

VL - 2015

JO - Advances in Materials Science and Engineering

JF - Advances in Materials Science and Engineering

M1 - 306708

ER -

A Turbidity Test Based Centrifugal Microfluidics Diagnostic System for Simultaneous Detection of HBV, HCV, and CMV

Abstract

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