Abstract
Wang L.-C., Chao D. and Chen E.-R. 1989. Acquired immunity in rats against Angiostrongylus cantonensis infection. International Journal for Parasitology 19: 617-620. Acquired immunity against Angiostrongylus cantonensis was induced by immunizing rats with somatic antigens from fifth-stage larvae and adult worms and live third-stage larvae. Rats immunized twice had significantly fewer worms than rats immunized three times. Fewer worms were recovered from rats immunized with 200 live third-stage larvae than from any other groups. Rats immunized with somatic antigens had higher enzyme-linked immunosorbent assay (ELISA) antibody levels than rats immunized with live larvae. Rats immunized with live third-stage larvae of Angiostrongylus cantonensis were more strongly protected against challenge infections (62-92%) than rats immunized with antigens extracted from fifth-stage larvae (0-30%) and adult worms (11-24%).
| Original language | English |
|---|---|
| Pages (from-to) | 617-620 |
| Number of pages | 4 |
| Journal | International Journal for Parasitology |
| Volume | 19 |
| Issue number | 6 |
| DOIs | |
| State | Published - 09 1989 |
| Externally published | Yes |
Keywords
- Angiostrongylus cantonensis
- ELISA
- acquired immunity
- stage antigens