Acting force comparison of microbeads and hemocytes in microchannel using optical tweezers system

Yung Chiang Chung; Yen Wen Hu; Tsong Long Hwang; Po Wen Chen; Fong Jian Sie

doi:10.1109/NEMS.2009.5068750

Acting force comparison of microbeads and hemocytes in microchannel using optical tweezers system

Yung Chiang Chung^*
, Yen Wen Hu
, Tsong Long Hwang
, Po Wen Chen
, Fong Jian Sie

^*Corresponding author for this work

School of Traditional Chinese Medicine

Ming Chi University of Technology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

An inverted-embedded optical tweezers system combining a micropump was assembled. The escaping velocities and acting forces of particles and hemocytes could be measured. After experiments and calculations, the escaping velocity of a 6 pm bead was 0.20 J.lmls and the trapping force was 0.012 pN when the power was 5 mW. The escaping velocity of a granulocyte was 0.80 J.lmls and the trapping force was 0.077 pN when the power was 60 mW. The escaping velocity of the blood cancer cell (K562) was 1.13 J.lmls and the trapping force was 0.13 pN when the power was 30 mW. The escaping velocity of a red blood cell was 0.67 J.lmls and the trapping force was 0.051 pN when the power was 60 mW. Considering the effect of the wall and the beads' sizes, one could modify the trapping force. The trapping force of 6 pm bead after modification was larger 1.3% than that before modification. The trapping force of 12.32 pm bead after modification was larger 3.5 % than that before modification. The distances between the beads and the wall actually affect the trapping force, but the differences were lower than 4 % in this research.

Original language	English
Title of host publication	4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009
Pages	1036-1039
Number of pages	4
DOIs	https://doi.org/10.1109/NEMS.2009.5068750
State	Published - 2009
Event	4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009 - Shenzhen, China Duration: 05 01 2009 → 08 01 2009

Publication series

Name	4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009

Conference

Conference	4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009
Country/Territory	China
City	Shenzhen
Period	05/01/09 → 08/01/09

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Acting force
Hemocyte
Microchannel
Optical tweezers

Access to Document

10.1109/NEMS.2009.5068750

Cite this

Chung, Y. C., Hu, Y. W., Hwang, T. L., Chen, P. W., & Sie, F. J. (2009). Acting force comparison of microbeads and hemocytes in microchannel using optical tweezers system. In 4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009 (pp. 1036-1039). Article 5068750 (4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009). https://doi.org/10.1109/NEMS.2009.5068750

@inproceedings{53d2a0d6dd904151a8b873d445df234b,

title = "Acting force comparison of microbeads and hemocytes in microchannel using optical tweezers system",

abstract = "An inverted-embedded optical tweezers system combining a micropump was assembled. The escaping velocities and acting forces of particles and hemocytes could be measured. After experiments and calculations, the escaping velocity of a 6 pm bead was 0.20 J.lmls and the trapping force was 0.012 pN when the power was 5 mW. The escaping velocity of a granulocyte was 0.80 J.lmls and the trapping force was 0.077 pN when the power was 60 mW. The escaping velocity of the blood cancer cell (K562) was 1.13 J.lmls and the trapping force was 0.13 pN when the power was 30 mW. The escaping velocity of a red blood cell was 0.67 J.lmls and the trapping force was 0.051 pN when the power was 60 mW. Considering the effect of the wall and the beads' sizes, one could modify the trapping force. The trapping force of 6 pm bead after modification was larger 1.3\% than that before modification. The trapping force of 12.32 pm bead after modification was larger 3.5 \% than that before modification. The distances between the beads and the wall actually affect the trapping force, but the differences were lower than 4 \% in this research.",

keywords = "Acting force, Hemocyte, Microchannel, Optical tweezers",

author = "Chung, \{Yung Chiang\} and Hu, \{Yen Wen\} and Hwang, \{Tsong Long\} and Chen, \{Po Wen\} and Sie, \{Fong Jian\}",

year = "2009",

doi = "10.1109/NEMS.2009.5068750",

language = "英语",

isbn = "9781424446308",

series = "4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009",

pages = "1036--1039",

booktitle = "4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009",

note = "4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009 ; Conference date: 05-01-2009 Through 08-01-2009",

}

Chung, YC, Hu, YW, Hwang, TL, Chen, PW & Sie, FJ 2009, Acting force comparison of microbeads and hemocytes in microchannel using optical tweezers system. in 4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009., 5068750, 4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009, pp. 1036-1039, 4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009, Shenzhen, China, 05/01/09. https://doi.org/10.1109/NEMS.2009.5068750

Acting force comparison of microbeads and hemocytes in microchannel using optical tweezers system. / Chung, Yung Chiang; Hu, Yen Wen; Hwang, Tsong Long et al.
4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009. 2009. p. 1036-1039 5068750 (4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Acting force comparison of microbeads and hemocytes in microchannel using optical tweezers system

AU - Chung, Yung Chiang

AU - Hu, Yen Wen

AU - Hwang, Tsong Long

AU - Chen, Po Wen

AU - Sie, Fong Jian

PY - 2009

Y1 - 2009

N2 - An inverted-embedded optical tweezers system combining a micropump was assembled. The escaping velocities and acting forces of particles and hemocytes could be measured. After experiments and calculations, the escaping velocity of a 6 pm bead was 0.20 J.lmls and the trapping force was 0.012 pN when the power was 5 mW. The escaping velocity of a granulocyte was 0.80 J.lmls and the trapping force was 0.077 pN when the power was 60 mW. The escaping velocity of the blood cancer cell (K562) was 1.13 J.lmls and the trapping force was 0.13 pN when the power was 30 mW. The escaping velocity of a red blood cell was 0.67 J.lmls and the trapping force was 0.051 pN when the power was 60 mW. Considering the effect of the wall and the beads' sizes, one could modify the trapping force. The trapping force of 6 pm bead after modification was larger 1.3% than that before modification. The trapping force of 12.32 pm bead after modification was larger 3.5 % than that before modification. The distances between the beads and the wall actually affect the trapping force, but the differences were lower than 4 % in this research.

AB - An inverted-embedded optical tweezers system combining a micropump was assembled. The escaping velocities and acting forces of particles and hemocytes could be measured. After experiments and calculations, the escaping velocity of a 6 pm bead was 0.20 J.lmls and the trapping force was 0.012 pN when the power was 5 mW. The escaping velocity of a granulocyte was 0.80 J.lmls and the trapping force was 0.077 pN when the power was 60 mW. The escaping velocity of the blood cancer cell (K562) was 1.13 J.lmls and the trapping force was 0.13 pN when the power was 30 mW. The escaping velocity of a red blood cell was 0.67 J.lmls and the trapping force was 0.051 pN when the power was 60 mW. Considering the effect of the wall and the beads' sizes, one could modify the trapping force. The trapping force of 6 pm bead after modification was larger 1.3% than that before modification. The trapping force of 12.32 pm bead after modification was larger 3.5 % than that before modification. The distances between the beads and the wall actually affect the trapping force, but the differences were lower than 4 % in this research.

KW - Acting force

KW - Hemocyte

KW - Microchannel

KW - Optical tweezers

UR - https://www.scopus.com/pages/publications/70349683206

U2 - 10.1109/NEMS.2009.5068750

DO - 10.1109/NEMS.2009.5068750

M3 - 会议稿件

AN - SCOPUS:70349683206

SN - 9781424446308

T3 - 4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009

SP - 1036

EP - 1039

BT - 4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009

T2 - 4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009

Y2 - 5 January 2009 through 8 January 2009

ER -

Chung YC, Hu YW, Hwang TL, Chen PW, Sie FJ. Acting force comparison of microbeads and hemocytes in microchannel using optical tweezers system. In 4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009. 2009. p. 1036-1039. 5068750. (4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009). doi: 10.1109/NEMS.2009.5068750

Acting force comparison of microbeads and hemocytes in microchannel using optical tweezers system

Abstract

Publication series

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UN SDGs

Keywords

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