Alveolar epithelial inter-alpha-trypsin inhibitor heavy chain 4 deficiency associated with senescence-regulated apoptosis by air pollution

Xiao Yue Chen, Po Hao Feng, Chia Li Han, Yu Teng Jheng, Chih Da Wu, Hsiu Chu Chou, Yi Ying Chen, Sheng Ming Wu, Kang Yun Lee, Han-Ping Kuo, Kian Fan Chung, Ta Chih Hsiao, Kuan Yuan Chen, Shu Chuan Ho, Ta Yuan Chang, Hsiao Chi Chuang*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

15 Scopus citations

Abstract

Capsule of main finding: The significance and novelty of this study are that ITIH4 regulates alveolar cell destruction by air pollution and thus could be an indicator of lung injury due to air pollution.

Original languageEnglish
Article number116863
JournalEnvironmental Pollution
Volume278
DOIs
StatePublished - 01 06 2021

Bibliographical note

Publisher Copyright:
© 2021 Elsevier Ltd

Keywords

  • Bronchoalveolar lavage fluid
  • Inflammation
  • Oxidative stress
  • PM
  • Particulate matter
  • Sirt1

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