An antibiotic biosensor platform for preclinical evaluation of drug release profile of nanocapsules

  • Chien Chong Hong*
  • , Chih Ying Wang
  • , Kuo Ti Peng
  • , I. Ming Chu
  • *Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

This paper presents an antibiotic biosensors platform for preclinical evaluation of drug release profile of nanocapsules. In this work, carbon nanotubes are used to modify the gold electrode surfaces to enhance the performance of the antibiotic biosensor platform. The results show that antibiotic nanocapsules significantly increase the drug release on the 4th day. And the release rate is 0.0258 μg/ml · hr. The drug release of antibiotic nanocapsules reached 24.98 μg/ml on the 7th day. The antibiotic biosensor platform for preclinical evaluation of drug release profile of nanocapsules presented in this work showed good performance in sensing of antibiotic Teoplanin drug samples.

Original languageEnglish
Title of host publication14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
Pages1670-1672
Number of pages3
StatePublished - 2010
Externally publishedYes
Event14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 - Groningen, Netherlands
Duration: 03 10 201007 10 2010

Publication series

Name14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
Volume3

Conference

Conference14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
Country/TerritoryNetherlands
CityGroningen
Period03/10/1007/10/10

Keywords

  • Antibiotic nanocapsule
  • Carbon nanotube electrode
  • Electrochemical biosensor
  • Preclinical evaluation

Fingerprint

Dive into the research topics of 'An antibiotic biosensor platform for preclinical evaluation of drug release profile of nanocapsules'. Together they form a unique fingerprint.

Cite this