An efficient voxel-driven system model for helical pinhole SPECT

Po Chia Huang*, Ching Han Hsu, Ing Tsung Hsiao, Kurt M. Lin

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


Conventionally, a pinhole SPECT acquires data by rotating the Gamma-camera in a circular orbit. However, such a acquisition method could merely scan a very limited field-of-view (FOV). For a longer object, it requires several circular acquisitions over various bed positions to cover the entire object. Multiple-bed acquisition also requires a high accurate movement control to avoid the overlapping or gap between any adjacent bed positions. In this work, we propose a voxel-driven (VD) system model (projection matrix) for iterative helical pinhole SPECT image reconstruction. The photon detection along helical trajectory can reduce acquisition time without multiple-bed overlapping and gap problems. However, the most challenging part for helical pinhole SPECT is the increase in image volume. For efficient computation and matrix storage reduction, the geometric symmetries derived from helical trajectory shall be fully utilized. By using a 16-fold symmetry derived from helical trajectory, the system matrix requires only 90 degrees information of projection geometry. A multi-threaded code can be implemented to accelerate the projection computation. The result for a two line sources phantom study shows that the VD model is efficient and suitable for iterative helical pinhole SPECT. The VD matrix could model the helical trajectory pinhole SPECT efficiently and handle a longer object without increasing any storage space of system matrix. The proposed model is also ready to be extended multiple-pinhole system for to better sensitivity as well as other fast reconstruction algorithms.

Original languageEnglish
Title of host publication2011 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2011
PublisherInstitute of Electrical and Electronics Engineers Inc.
Number of pages4
ISBN (Print)9781467301183
StatePublished - 2011
Event2011 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2011 - Valencia, Spain
Duration: 23 10 201129 10 2011

Publication series

NameIEEE Nuclear Science Symposium Conference Record
ISSN (Print)1095-7863


Conference2011 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2011


  • Helical Pinhole SPECT
  • Iterative Image Reconstruction
  • Pinhole SPECT
  • Voxel-Driven Model


Dive into the research topics of 'An efficient voxel-driven system model for helical pinhole SPECT'. Together they form a unique fingerprint.

Cite this