An epidemic of plasmids? Dissemination of extended-spectrum cephalosporinases among Salmonella and other Enterobacteriaceae

Lin Hui Su; Chishih Chu; Axel Cloeckaert; Cheng Hsun Chiu

doi:10.1111/j.1574-695X.2007.00360.x

An epidemic of plasmids? Dissemination of extended-spectrum cephalosporinases among Salmonella and other Enterobacteriaceae

Lin Hui Su
, Chishih Chu
, Axel Cloeckaert
, Cheng Hsun Chiu^*

^*Corresponding author for this work

Research output: Contribution to journal › Short survey › peer-review

34 Scopus citations

Abstract

CTX-M- and AmpC-type β-lactamases comprise the two most rapidly growing populations among the extended-spectrum cephalosporinases. The evolution and dissemination of resistance genes encoding these enzymes occur mostly through the transmission of plasmids. The high prevalence of clinical isolates of Enterobacteriaceae producing the plasmid-mediated extended-spectrum cephalosporinases resembles an epidemic of plasmids, and has generated serious therapeutic problems. This review describes the emergence and worldwide spread of various classes of plasmid-mediated extended-spectrum cephalosporinases in Salmonella and other Enterobacteriaceae, the transfer mechanism of the plasmids, detection methods, and therapeutic choices.

Original language	English
Pages (from-to)	155-168
Number of pages	14
Journal	FEMS Immunology and Medical Microbiology
Volume	52
Issue number	2
DOIs	https://doi.org/10.1111/j.1574-695X.2007.00360.x
State	Published - 03 2008
Externally published	Yes

Keywords

AmpC
Antimicrobial resistance
Enterobacteriaceae
Extended-spectrum β-lactamase
Plasmid
Salmonella

Access to Document

10.1111/j.1574-695X.2007.00360.x

Cite this

@article{26604e3515964d3c98421c5a50f3d313,

title = "An epidemic of plasmids? Dissemination of extended-spectrum cephalosporinases among Salmonella and other Enterobacteriaceae",

abstract = "CTX-M- and AmpC-type β-lactamases comprise the two most rapidly growing populations among the extended-spectrum cephalosporinases. The evolution and dissemination of resistance genes encoding these enzymes occur mostly through the transmission of plasmids. The high prevalence of clinical isolates of Enterobacteriaceae producing the plasmid-mediated extended-spectrum cephalosporinases resembles an epidemic of plasmids, and has generated serious therapeutic problems. This review describes the emergence and worldwide spread of various classes of plasmid-mediated extended-spectrum cephalosporinases in Salmonella and other Enterobacteriaceae, the transfer mechanism of the plasmids, detection methods, and therapeutic choices.",

keywords = "AmpC, Antimicrobial resistance, Enterobacteriaceae, Extended-spectrum β-lactamase, Plasmid, Salmonella",

author = "Su, \{Lin Hui\} and Chishih Chu and Axel Cloeckaert and Chiu, \{Cheng Hsun\}",

year = "2008",

month = mar,

doi = "10.1111/j.1574-695X.2007.00360.x",

language = "英语",

volume = "52",

pages = "155--168",

journal = "FEMS Immunology and Medical Microbiology",

issn = "0928-8244",

publisher = "Wiley-Blackwell Publishing Ltd",

number = "2",

}

TY - JOUR

T1 - An epidemic of plasmids? Dissemination of extended-spectrum cephalosporinases among Salmonella and other Enterobacteriaceae

AU - Su, Lin Hui

AU - Chu, Chishih

AU - Cloeckaert, Axel

AU - Chiu, Cheng Hsun

PY - 2008/3

Y1 - 2008/3

N2 - CTX-M- and AmpC-type β-lactamases comprise the two most rapidly growing populations among the extended-spectrum cephalosporinases. The evolution and dissemination of resistance genes encoding these enzymes occur mostly through the transmission of plasmids. The high prevalence of clinical isolates of Enterobacteriaceae producing the plasmid-mediated extended-spectrum cephalosporinases resembles an epidemic of plasmids, and has generated serious therapeutic problems. This review describes the emergence and worldwide spread of various classes of plasmid-mediated extended-spectrum cephalosporinases in Salmonella and other Enterobacteriaceae, the transfer mechanism of the plasmids, detection methods, and therapeutic choices.

AB - CTX-M- and AmpC-type β-lactamases comprise the two most rapidly growing populations among the extended-spectrum cephalosporinases. The evolution and dissemination of resistance genes encoding these enzymes occur mostly through the transmission of plasmids. The high prevalence of clinical isolates of Enterobacteriaceae producing the plasmid-mediated extended-spectrum cephalosporinases resembles an epidemic of plasmids, and has generated serious therapeutic problems. This review describes the emergence and worldwide spread of various classes of plasmid-mediated extended-spectrum cephalosporinases in Salmonella and other Enterobacteriaceae, the transfer mechanism of the plasmids, detection methods, and therapeutic choices.

KW - AmpC

KW - Antimicrobial resistance

KW - Enterobacteriaceae

KW - Extended-spectrum β-lactamase

KW - Plasmid

KW - Salmonella

UR - https://www.scopus.com/pages/publications/39049169165

U2 - 10.1111/j.1574-695X.2007.00360.x

DO - 10.1111/j.1574-695X.2007.00360.x

M3 - 短篇评述

C2 - 18093140

AN - SCOPUS:39049169165

SN - 0928-8244

VL - 52

SP - 155

EP - 168

JO - FEMS Immunology and Medical Microbiology

JF - FEMS Immunology and Medical Microbiology

IS - 2

ER -

An epidemic of plasmids? Dissemination of extended-spectrum cephalosporinases among Salmonella and other Enterobacteriaceae

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this