An integrated microfluidic chip for the study of metastasis and angiogenesis

Yong Yu Hsu; Kuo Wei Chang; Tse Shao Chen; Kang Yun Lee; Chen Shien Liu

doi:10.1109/NEMS.2014.6908842

An integrated microfluidic chip for the study of metastasis and angiogenesis

Yong Yu Hsu^*, Kuo Wei Chang, Tse Shao Chen, Kang Yun Lee, Chen Shien Liu

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

2 Scopus citations

Abstract

Cancer is a seriously disease in the modern, and lung cancer is one of the cancers with the high fatality rate. There are some clinical strategies to cure cancer, like surgery, radiation and chemotherapy. Even we have many solutions to treat with cancer, but they are still with some shortages. According to the literature survey and clinical experts, the ability of a tumor to achieve vascularization is an essential hallmark of cancer biology. Recently, cell based systems has become the target to develop new cancer therapy for the inhibition of tumor angiogenesis. In this research, we demonstrated a platform which is based on the concentration gradient generator and DEP cell pattern technology, to study the relationship between angiogenesis and tumor cell.

Original language	English
Title of host publication	9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	426-429
Number of pages	4
ISBN (Electronic)	9781479947270
DOIs	https://doi.org/10.1109/NEMS.2014.6908842
State	Published - 23 09 2014
Externally published	Yes
Event	9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014 - Waikiki Beach, United States Duration: 13 04 2014 → 16 04 2014

Publication series

Name	9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014

Conference

Conference	9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014
Country/Territory	United States
City	Waikiki Beach
Period	13/04/14 → 16/04/14

Bibliographical note

Publisher Copyright:
© 2014 IEEE.

Keywords

Lung cancer
angiogenesis
extracellular matrix (ECM)
pattern
vascular endothelial cell

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1109/NEMS.2014.6908842

Cite this

Hsu, Y. Y., Chang, K. W., Chen, T. S., Lee, K. Y., & Liu, C. S. (2014). An integrated microfluidic chip for the study of metastasis and angiogenesis. In 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014 (pp. 426-429). Article 6908842 (9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/NEMS.2014.6908842

Hsu, Yong Yu ; Chang, Kuo Wei ; Chen, Tse Shao et al. / An integrated microfluidic chip for the study of metastasis and angiogenesis. 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014. Institute of Electrical and Electronics Engineers Inc., 2014. pp. 426-429 (9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014).

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title = "An integrated microfluidic chip for the study of metastasis and angiogenesis",

abstract = "Cancer is a seriously disease in the modern, and lung cancer is one of the cancers with the high fatality rate. There are some clinical strategies to cure cancer, like surgery, radiation and chemotherapy. Even we have many solutions to treat with cancer, but they are still with some shortages. According to the literature survey and clinical experts, the ability of a tumor to achieve vascularization is an essential hallmark of cancer biology. Recently, cell based systems has become the target to develop new cancer therapy for the inhibition of tumor angiogenesis. In this research, we demonstrated a platform which is based on the concentration gradient generator and DEP cell pattern technology, to study the relationship between angiogenesis and tumor cell.",

keywords = "Lung cancer, angiogenesis, extracellular matrix (ECM), pattern, vascular endothelial cell",

author = "Hsu, {Yong Yu} and Chang, {Kuo Wei} and Chen, {Tse Shao} and Lee, {Kang Yun} and Liu, {Chen Shien}",

note = "Publisher Copyright: {\textcopyright} 2014 IEEE.; 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014 ; Conference date: 13-04-2014 Through 16-04-2014",

year = "2014",

month = sep,

day = "23",

doi = "10.1109/NEMS.2014.6908842",

language = "英语",

series = "9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014",

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Hsu, YY, Chang, KW, Chen, TS, Lee, KY & Liu, CS 2014, An integrated microfluidic chip for the study of metastasis and angiogenesis. in 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014., 6908842, 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014, Institute of Electrical and Electronics Engineers Inc., pp. 426-429, 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014, Waikiki Beach, United States, 13/04/14. https://doi.org/10.1109/NEMS.2014.6908842

An integrated microfluidic chip for the study of metastasis and angiogenesis. / Hsu, Yong Yu; Chang, Kuo Wei; Chen, Tse Shao et al.
9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014. Institute of Electrical and Electronics Engineers Inc., 2014. p. 426-429 6908842 (9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - An integrated microfluidic chip for the study of metastasis and angiogenesis

AU - Hsu, Yong Yu

AU - Chang, Kuo Wei

AU - Chen, Tse Shao

AU - Lee, Kang Yun

AU - Liu, Chen Shien

PY - 2014/9/23

Y1 - 2014/9/23

N2 - Cancer is a seriously disease in the modern, and lung cancer is one of the cancers with the high fatality rate. There are some clinical strategies to cure cancer, like surgery, radiation and chemotherapy. Even we have many solutions to treat with cancer, but they are still with some shortages. According to the literature survey and clinical experts, the ability of a tumor to achieve vascularization is an essential hallmark of cancer biology. Recently, cell based systems has become the target to develop new cancer therapy for the inhibition of tumor angiogenesis. In this research, we demonstrated a platform which is based on the concentration gradient generator and DEP cell pattern technology, to study the relationship between angiogenesis and tumor cell.

AB - Cancer is a seriously disease in the modern, and lung cancer is one of the cancers with the high fatality rate. There are some clinical strategies to cure cancer, like surgery, radiation and chemotherapy. Even we have many solutions to treat with cancer, but they are still with some shortages. According to the literature survey and clinical experts, the ability of a tumor to achieve vascularization is an essential hallmark of cancer biology. Recently, cell based systems has become the target to develop new cancer therapy for the inhibition of tumor angiogenesis. In this research, we demonstrated a platform which is based on the concentration gradient generator and DEP cell pattern technology, to study the relationship between angiogenesis and tumor cell.

KW - Lung cancer

KW - angiogenesis

KW - extracellular matrix (ECM)

KW - pattern

KW - vascular endothelial cell

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BT - 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014

PB - Institute of Electrical and Electronics Engineers Inc.

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Y2 - 13 April 2014 through 16 April 2014

ER -

Hsu YY, Chang KW, Chen TS, Lee KY, Liu CS. An integrated microfluidic chip for the study of metastasis and angiogenesis. In 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014. Institute of Electrical and Electronics Engineers Inc. 2014. p. 426-429. 6908842. (9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014). doi: 10.1109/NEMS.2014.6908842

An integrated microfluidic chip for the study of metastasis and angiogenesis

Abstract

Publication series

Conference

Bibliographical note

Keywords

UN SDGs

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