An integrated microfluidic system for bacteria detection by using mannose-binding lectin

Ju Ching Yu, Wen Hsin Chang, Yung Shing Wang, Mel S. Lee, Kuo Ti Peng, Gwo Bin Lee*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Periprosthetic joint infection (PJI) is one of the most challenging complications after arthroplasty. It is challenging in clinical practice to fight methicillin-resistant Staphylococcus aureus (MRSA) PJI. In this work, a new integrated microfluidic system by utilizing mannose-binding lectin (MBL) coated beads and polymerase chain reaction (PCR) is therefore reported for detection of bacteria. It is the first time that antibiotics-resistant and biofilm-related bacteria could be diagnosed on an integrated microfluidic system.

Original languageEnglish
Title of host publication20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
PublisherChemical and Biological Microsystems Society
Pages631-632
Number of pages2
ISBN (Electronic)9780979806490
StatePublished - 2016
Externally publishedYes
Event20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland
Duration: 09 10 201613 10 2016

Publication series

Name20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016

Conference

Conference20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
Country/TerritoryIreland
CityDublin
Period09/10/1613/10/16

Keywords

  • Mannose-binding lectin
  • Microfluidics
  • Periprosthetic joint infection

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