TY - GEN
T1 - An integrated optical sensor for online monitoring of lactate concentration
AU - Cai, Haoyuan
AU - Wu, Min Hsien
AU - Cui, Zheng
PY - 2005
Y1 - 2005
N2 - A microfluidic device with integrated optical fibres was developed for online monitoring of lactate. The device consists of a SU-8 waveguide, microfluidic channels and grooves for the insertion of optical fibers. Different channel widths (50~300μm) were tested. A wide range of flow rates were applied to investigate the influence of flow rate on signal fluctuations. The separation between optical fiber sensor and microfluidic channel and the width of fluidic channel have been optimized to maximize the detection sensitivity. Compared with conventional lactate detection, the device has higher accuracy, relatively low limit of detection (50mg/L) and reasonably fast response time (100 sec). The fabrication of device is simple and low cost. The present work has provided some fundamental data for further system optimization to meet specific detection requirements.
AB - A microfluidic device with integrated optical fibres was developed for online monitoring of lactate. The device consists of a SU-8 waveguide, microfluidic channels and grooves for the insertion of optical fibers. Different channel widths (50~300μm) were tested. A wide range of flow rates were applied to investigate the influence of flow rate on signal fluctuations. The separation between optical fiber sensor and microfluidic channel and the width of fluidic channel have been optimized to maximize the detection sensitivity. Compared with conventional lactate detection, the device has higher accuracy, relatively low limit of detection (50mg/L) and reasonably fast response time (100 sec). The fabrication of device is simple and low cost. The present work has provided some fundamental data for further system optimization to meet specific detection requirements.
UR - http://www.scopus.com/inward/record.url?scp=33847263166&partnerID=8YFLogxK
U2 - 10.1109/ICSENS.2005.1597862
DO - 10.1109/ICSENS.2005.1597862
M3 - 会议稿件
AN - SCOPUS:33847263166
SN - 0780390563
SN - 9780780390560
T3 - Proceedings of IEEE Sensors
SP - 967
EP - 970
BT - Proceedings of the Fourth IEEE Conference on Sensors 2005
T2 - Fourth IEEE Conference on Sensors 2005
Y2 - 31 October 2005 through 3 November 2005
ER -