Ancient DNA indicates human population shifts and admixture in northern and southern China

Melinda A. Yang; Xuechun Fan; Bo Sun; Chungyu Chen; Jianfeng Lang; Ying Chin Ko; Cheng Hwa Tsang; Hunglin Chiu; Tianyi Wang; Qingchuan Bao; Xiaohong Wu; Mateja Hajdinjak; Albert Min Shan Ko; Manyu Ding; Peng Cao; Ruowei Yang; Feng Liu; Birgit Nickel; Qingyan Dai; Xiaotian Feng; Lizhao Zhang; Chengkai Sun; Chao Ning; Wen Zeng; Yongsheng Zhao; Ming Zhang; Xing Gao; Yinqiu Cui; David Reich; Mark Stoneking; Qiaomei Fu

doi:10.1126/science.aba0909

Ancient DNA indicates human population shifts and admixture in northern and southern China

Melinda A. Yang, Xuechun Fan, Bo Sun, Chungyu Chen, Jianfeng Lang, Ying Chin Ko, Cheng Hwa Tsang, Hunglin Chiu, Tianyi Wang, Qingchuan Bao, Xiaohong Wu, Mateja Hajdinjak, Albert Min Shan Ko, Manyu Ding, Peng Cao, Ruowei Yang, Feng Liu, Birgit Nickel, Qingyan Dai, Xiaotian FengLizhao Zhang, Chengkai Sun, Chao Ning, Wen Zeng, Yongsheng Zhao, Ming Zhang, Xing Gao, Yinqiu Cui, David Reich, Mark Stoneking, Qiaomei Fu^*

^*Corresponding author for this work

Research output: Contribution to journal › Journal Article › peer-review

206 Scopus citations

Abstract

Human genetic history in East Asia is poorly understood. To clarify population relationships, we obtained genome-wide data from 26 ancient individuals from northern and southern East Asia spanning 9500 to 300 years ago. Genetic differentiation in this region was higher in the past than the present, which reflects a major episode of admixture involving northern East Asian ancestry spreading across southern East Asia after the Neolithic, thereby transforming the genetic ancestry of southern China. Mainland southern East Asian and Taiwan Strait island samples from the Neolithic show clear connections with modern and ancient individuals with Austronesian-related ancestry, which supports an origin in southern China for proto-Austronesians. Connections among Neolithic coastal groups from Siberia and Japan to Vietnam indicate that migration and gene flow played an important role in the prehistory of coastal Asia.

Original language	English
Pages (from-to)	282-288
Number of pages	7
Journal	Science
Volume	369
Issue number	6501
DOIs	https://doi.org/10.1126/science.aba0909
State	Published - 17 07 2020
Externally published	Yes

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© 2020 American Association for the Advancement of Science. All rights reserved.

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Yang, M. A., Fan, X., Sun, B., Chen, C., Lang, J., Ko, Y. C., Tsang, C. H., Chiu, H., Wang, T., Bao, Q., Wu, X., Hajdinjak, M., Ko, A. M. S., Ding, M., Cao, P., Yang, R., Liu, F., Nickel, B., Dai, Q., ... Fu, Q. (2020). Ancient DNA indicates human population shifts and admixture in northern and southern China. Science, 369(6501), 282-288. https://doi.org/10.1126/science.aba0909

@article{9aaea506792540aeab5ccedd87560e8a,

title = "Ancient DNA indicates human population shifts and admixture in northern and southern China",

abstract = "Human genetic history in East Asia is poorly understood. To clarify population relationships, we obtained genome-wide data from 26 ancient individuals from northern and southern East Asia spanning 9500 to 300 years ago. Genetic differentiation in this region was higher in the past than the present, which reflects a major episode of admixture involving northern East Asian ancestry spreading across southern East Asia after the Neolithic, thereby transforming the genetic ancestry of southern China. Mainland southern East Asian and Taiwan Strait island samples from the Neolithic show clear connections with modern and ancient individuals with Austronesian-related ancestry, which supports an origin in southern China for proto-Austronesians. Connections among Neolithic coastal groups from Siberia and Japan to Vietnam indicate that migration and gene flow played an important role in the prehistory of coastal Asia.",

author = "Yang, {Melinda A.} and Xuechun Fan and Bo Sun and Chungyu Chen and Jianfeng Lang and Ko, {Ying Chin} and Tsang, {Cheng Hwa} and Hunglin Chiu and Tianyi Wang and Qingchuan Bao and Xiaohong Wu and Mateja Hajdinjak and Ko, {Albert Min Shan} and Manyu Ding and Peng Cao and Ruowei Yang and Feng Liu and Birgit Nickel and Qingyan Dai and Xiaotian Feng and Lizhao Zhang and Chengkai Sun and Chao Ning and Wen Zeng and Yongsheng Zhao and Ming Zhang and Xing Gao and Yinqiu Cui and David Reich and Mark Stoneking and Qiaomei Fu",

year = "2020",

month = jul,

day = "17",

doi = "10.1126/science.aba0909",

language = "英语",

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Yang, MA, Fan, X, Sun, B, Chen, C, Lang, J, Ko, YC, Tsang, CH, Chiu, H, Wang, T, Bao, Q, Wu, X, Hajdinjak, M, Ko, AMS, Ding, M, Cao, P, Yang, R, Liu, F, Nickel, B, Dai, Q, Feng, X, Zhang, L, Sun, C, Ning, C, Zeng, W, Zhao, Y, Zhang, M, Gao, X, Cui, Y, Reich, D, Stoneking, M & Fu, Q 2020, 'Ancient DNA indicates human population shifts and admixture in northern and southern China', Science, vol. 369, no. 6501, pp. 282-288. https://doi.org/10.1126/science.aba0909

TY - JOUR

T1 - Ancient DNA indicates human population shifts and admixture in northern and southern China

AU - Yang, Melinda A.

AU - Fan, Xuechun

AU - Sun, Bo

AU - Chen, Chungyu

AU - Lang, Jianfeng

AU - Ko, Ying Chin

AU - Tsang, Cheng Hwa

AU - Chiu, Hunglin

AU - Wang, Tianyi

AU - Bao, Qingchuan

AU - Wu, Xiaohong

AU - Hajdinjak, Mateja

AU - Ko, Albert Min Shan

AU - Ding, Manyu

AU - Cao, Peng

AU - Yang, Ruowei

AU - Liu, Feng

AU - Nickel, Birgit

AU - Dai, Qingyan

AU - Feng, Xiaotian

AU - Zhang, Lizhao

AU - Sun, Chengkai

AU - Ning, Chao

AU - Zeng, Wen

AU - Zhao, Yongsheng

AU - Zhang, Ming

AU - Gao, Xing

AU - Cui, Yinqiu

AU - Reich, David

AU - Stoneking, Mark

AU - Fu, Qiaomei

PY - 2020/7/17

Y1 - 2020/7/17

N2 - Human genetic history in East Asia is poorly understood. To clarify population relationships, we obtained genome-wide data from 26 ancient individuals from northern and southern East Asia spanning 9500 to 300 years ago. Genetic differentiation in this region was higher in the past than the present, which reflects a major episode of admixture involving northern East Asian ancestry spreading across southern East Asia after the Neolithic, thereby transforming the genetic ancestry of southern China. Mainland southern East Asian and Taiwan Strait island samples from the Neolithic show clear connections with modern and ancient individuals with Austronesian-related ancestry, which supports an origin in southern China for proto-Austronesians. Connections among Neolithic coastal groups from Siberia and Japan to Vietnam indicate that migration and gene flow played an important role in the prehistory of coastal Asia.

AB - Human genetic history in East Asia is poorly understood. To clarify population relationships, we obtained genome-wide data from 26 ancient individuals from northern and southern East Asia spanning 9500 to 300 years ago. Genetic differentiation in this region was higher in the past than the present, which reflects a major episode of admixture involving northern East Asian ancestry spreading across southern East Asia after the Neolithic, thereby transforming the genetic ancestry of southern China. Mainland southern East Asian and Taiwan Strait island samples from the Neolithic show clear connections with modern and ancient individuals with Austronesian-related ancestry, which supports an origin in southern China for proto-Austronesians. Connections among Neolithic coastal groups from Siberia and Japan to Vietnam indicate that migration and gene flow played an important role in the prehistory of coastal Asia.

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U2 - 10.1126/science.aba0909

DO - 10.1126/science.aba0909

M3 - 文章

C2 - 32409524

AN - SCOPUS:85087796796

SN - 0036-8075

VL - 369

SP - 282

EP - 288

JO - Science

JF - Science

IS - 6501

ER -

Ancient DNA indicates human population shifts and admixture in northern and southern China

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