Anemia in Kawasaki Disease

Ying Hsien Huang, Ho Chang Kuo*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Kawasaki disease (KD) is the most common acute coronary vasculitis syndrome that mainly affects genetically susceptible kids under 5 years of age. Aside from the standard diagnostic five criteria, patients with KD may also experience a variety of nonspecific clinical symptoms and signs. Anemia is the most common clinical feature in KD patients. In 2001, the scientists have the discovery of a liver-derived peptide hormone named as hepcidin began revolutionizing the understanding of anemia’s relation to a number of inflammatory diseases, including KD. This chapter focuses on hepcidin-induced iron deficiency’s relation to transient hyposideremia, anemia, and disease outcomes in KD patients, and goes on to suggest possible routes of KD study.

Original languageEnglish
Title of host publicationKawasaki Disease
PublisherSpringer Nature
Pages147-153
Number of pages7
ISBN (Electronic)9789811929441
ISBN (Print)9789811929434
DOIs
StatePublished - 01 01 2022

Bibliographical note

Publisher Copyright:
© The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2022.

Keywords

  • Anemia
  • HAMP
  • Hepcidin
  • Iron
  • Kawasaki disease

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