Anti-inflammatory diterpenoids from croton tonkinensis

Ping Chung Kuo; Mei Lin Yang; Tsong Long Hwang; Yuan Yu Lai; Yue Chiun Li; Tran Dinh Thang; Tian Shung Wu

doi:10.1021/np300699f

Anti-inflammatory diterpenoids from croton tonkinensis

Ping Chung Kuo
, Mei Lin Yang
, Tsong Long Hwang
, Yuan Yu Lai
, Yue Chiun Li
, Tran Dinh Thang
, Tian Shung Wu^*

^*Corresponding author for this work

School of Traditional Chinese Medicine

Research output: Contribution to journal › Journal Article › peer-review

53 Scopus citations

Abstract

Phytochemical investigation of the methanolic extract of Croton tonkinensis afforded two known kauranes (1, 2), eight new ent-kauranes (3-10), and 16 known ent-kauranetype diterpenoids (12-27). In addition, 30 known compounds were identified by comparison of their physical and spectroscopic data with reported data. Among the isolated compounds, ent-18-acetoxykaur-16-en-15-one (20) displayed the most significant inhibition of superoxide anion generation and elastase release.

Original language	English
Pages (from-to)	230-236
Number of pages	7
Journal	Journal of Natural Products
Volume	76
Issue number	2
DOIs	https://doi.org/10.1021/np300699f
State	Published - 22 02 2013

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title = "Anti-inflammatory diterpenoids from croton tonkinensis",

abstract = "Phytochemical investigation of the methanolic extract of Croton tonkinensis afforded two known kauranes (1, 2), eight new ent-kauranes (3-10), and 16 known ent-kauranetype diterpenoids (12-27). In addition, 30 known compounds were identified by comparison of their physical and spectroscopic data with reported data. Among the isolated compounds, ent-18-acetoxykaur-16-en-15-one (20) displayed the most significant inhibition of superoxide anion generation and elastase release.",

author = "Kuo, \{Ping Chung\} and Yang, \{Mei Lin\} and Hwang, \{Tsong Long\} and Lai, \{Yuan Yu\} and Li, \{Yue Chiun\} and Thang, \{Tran Dinh\} and Wu, \{Tian Shung\}",

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AU - Kuo, Ping Chung

AU - Yang, Mei Lin

AU - Hwang, Tsong Long

AU - Lai, Yuan Yu

AU - Li, Yue Chiun

AU - Thang, Tran Dinh

AU - Wu, Tian Shung

PY - 2013/2/22

Y1 - 2013/2/22

N2 - Phytochemical investigation of the methanolic extract of Croton tonkinensis afforded two known kauranes (1, 2), eight new ent-kauranes (3-10), and 16 known ent-kauranetype diterpenoids (12-27). In addition, 30 known compounds were identified by comparison of their physical and spectroscopic data with reported data. Among the isolated compounds, ent-18-acetoxykaur-16-en-15-one (20) displayed the most significant inhibition of superoxide anion generation and elastase release.

AB - Phytochemical investigation of the methanolic extract of Croton tonkinensis afforded two known kauranes (1, 2), eight new ent-kauranes (3-10), and 16 known ent-kauranetype diterpenoids (12-27). In addition, 30 known compounds were identified by comparison of their physical and spectroscopic data with reported data. Among the isolated compounds, ent-18-acetoxykaur-16-en-15-one (20) displayed the most significant inhibition of superoxide anion generation and elastase release.

UR - https://www.scopus.com/pages/publications/84876741940

U2 - 10.1021/np300699f

DO - 10.1021/np300699f

M3 - 文章

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AN - SCOPUS:84876741940

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SP - 230

EP - 236

JO - Journal of Natural Products

JF - Journal of Natural Products

IS - 2

ER -

Anti-inflammatory diterpenoids from croton tonkinensis

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