Antibacterial property and cytotoxicity of a poly(lactic acid)/nanosilver-doped multiwall carbon nanotube nanocomposite

Chi Hui Tsou*, Wei Hua Yao, Yi Cheng Lu, Chih Yuan Tsou, Chin San Wu, Jian Chen, Ruo Yao Wang, Chao Chin Su, Wei Song Hung, Manuel De Guzman, Maw Cherng Suen

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

50 Scopus citations

Abstract

A novel method was used to synthesize a nanosilver-doped multiwall carbon nanotube (MWCNT-Ag), and subsequently, the novel poly(lactic acid) (PLA)- and MWCNT-Ag-based biocompatible and antimicrobial nanocomposites were prepared by melt blending. Based on energy dispersive X-ray spectrometry images, an MWCNT-Ag was successfully synthesized. The effect of the MWCNT-Ag on the PLA bionanocomposites was investigated by evaluating their thermal and mechanical properties, antifungal activity, and cytotoxicity. The nanocomposites exhibited a high degree of biocompatibility with the MWCNT-Ag content, which was less than 0.3 phr. Furthermore, tensile strength testing, thermogravimetric analysis, differential scanning calorimetry, and antibacterial evaluation revealed that the tensile strength, thermostability, glass transition temperature, and antibacterial properties were enhanced by increasing the MWCNT-Ag content. Finally, hydrolysis analysis indicated that the low MWCNT-Ag content could increase the packing density of PLA.

Original languageEnglish
Article number100
JournalPolymers
Volume9
Issue number3
DOIs
StatePublished - 2017
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2017 by the authors.

Keywords

  • Antibacterial property
  • Bionanocomposites
  • Cytotoxicity
  • Nanosilver-doped multiwall carbon nanotube
  • Poly(lactic acid)

Fingerprint

Dive into the research topics of 'Antibacterial property and cytotoxicity of a poly(lactic acid)/nanosilver-doped multiwall carbon nanotube nanocomposite'. Together they form a unique fingerprint.

Cite this