TY - JOUR
T1 - Antimicrobial resistance burden in India and Germany in 2022
T2 - A systematic analysis along with One Health perspective
AU - Gunjan,
AU - Pandey, Ramendra Pati
AU - Himanshu,
AU - Kaur, Kirtanjot
AU - Ahmad, Saheem
AU - Mukherjee, Riya
AU - Chang, Chung Ming
N1 - © 2024 The Authors.
PY - 2024/9/30
Y1 - 2024/9/30
N2 - Globally increasing antibiotic resistance has been linked to the extensive use of antibiotics in medical, veterinary, and agricultural Practices. This study aims to investigate the correlations of antimicrobial-resistant of various pathogens in three compartments: humans, animals and the environment in India and Germany. A systematic search was carried out in Medline via PubMed, Google Scholar, and science direct, including studies published in 2022. Out of 532 papers, 24 were considered for meta-analysis. Our findings reveals that in India, β-lactam is highly resistant in animals. Quinolone, on the other hand, was highly resistant in humans. In the environmental sectors, aminoglycosides and β-lactams is resistant. While in Germany, β-lactam resistance is high across all three sectors. However, E. coli was the most frequent and resistant pathogen in both countries, with significant resistance to β-lactams and cephalosporins across all compartments. These results underscore the critical need for monitoring antibiotic resistance patterns and developing targeted antibiotic regimens. A One Health-based intervention strategy is essential to mitigate the spread of AMR and improve health outcomes globally.
AB - Globally increasing antibiotic resistance has been linked to the extensive use of antibiotics in medical, veterinary, and agricultural Practices. This study aims to investigate the correlations of antimicrobial-resistant of various pathogens in three compartments: humans, animals and the environment in India and Germany. A systematic search was carried out in Medline via PubMed, Google Scholar, and science direct, including studies published in 2022. Out of 532 papers, 24 were considered for meta-analysis. Our findings reveals that in India, β-lactam is highly resistant in animals. Quinolone, on the other hand, was highly resistant in humans. In the environmental sectors, aminoglycosides and β-lactams is resistant. While in Germany, β-lactam resistance is high across all three sectors. However, E. coli was the most frequent and resistant pathogen in both countries, with significant resistance to β-lactams and cephalosporins across all compartments. These results underscore the critical need for monitoring antibiotic resistance patterns and developing targeted antibiotic regimens. A One Health-based intervention strategy is essential to mitigate the spread of AMR and improve health outcomes globally.
KW - Antibiotics
KW - Antimicrobial resistance
KW - Germany
KW - India
KW - One health
KW - Systematic review
UR - https://www.scopus.com/pages/publications/85204398301
U2 - 10.1016/j.heliyon.2024.e37910
DO - 10.1016/j.heliyon.2024.e37910
M3 - 文章
C2 - 39328565
AN - SCOPUS:85204398301
SN - 2405-8440
VL - 10
SP - e37910
JO - Heliyon
JF - Heliyon
IS - 18
M1 - e37910
ER -