Antioxidant principles from Ephemerantha lonchophylla

Hon Yi Chen; Ming Shi Shiao; Yu Lin Huang; Chien Chang Shen; Yun Lian Lin; Yueh Hsiung Kuo; Chien Chih Chen

doi:10.1021/np990025f

Antioxidant principles from Ephemerantha lonchophylla

Hon Yi Chen, Ming Shi Shiao, Yu Lin Huang, Chien Chang Shen, Yun Lian Lin, Yueh Hsiung Kuo, Chien Chih Chen^*

^*Corresponding author for this work

Research output: Contribution to journal › Journal Article › peer-review

37 Scopus citations

Abstract

One dihydrostilbene and three phenanthrene antioxidants were isolated from an ethanolic extract of the Chinese herbal Ephemerantha lonchophylla. One of these compounds, ephemeranthone (4) is a new natural product. Denbinobin (1) and 3-methylgigantol (3) have been previously isolated from this plant, and 3-ethoxy-5-hydroxy-7-methoxy-1,4-phenanthraquinone (2) is an artifact. The structures of these compounds were determined by spectroscopic analysis. The antioxidative activities for inhibiting human low density lipoprotein oxidation in vitro of compounds 1-4 were determined, and only 4 was active (5.3 times that of probucol).

Original language	English
Pages (from-to)	1225-1227
Number of pages	3
Journal	Journal of Natural Products
Volume	62
Issue number	9
DOIs	https://doi.org/10.1021/np990025f
State	Published - 09 1999
Externally published	Yes

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title = "Antioxidant principles from Ephemerantha lonchophylla",

abstract = "One dihydrostilbene and three phenanthrene antioxidants were isolated from an ethanolic extract of the Chinese herbal Ephemerantha lonchophylla. One of these compounds, ephemeranthone (4) is a new natural product. Denbinobin (1) and 3-methylgigantol (3) have been previously isolated from this plant, and 3-ethoxy-5-hydroxy-7-methoxy-1,4-phenanthraquinone (2) is an artifact. The structures of these compounds were determined by spectroscopic analysis. The antioxidative activities for inhibiting human low density lipoprotein oxidation in vitro of compounds 1-4 were determined, and only 4 was active (5.3 times that of probucol).",

author = "Chen, {Hon Yi} and Shiao, {Ming Shi} and Huang, {Yu Lin} and Shen, {Chien Chang} and Lin, {Yun Lian} and Kuo, {Yueh Hsiung} and Chen, {Chien Chih}",

year = "1999",

month = sep,

doi = "10.1021/np990025f",

language = "英语",

volume = "62",

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publisher = "American Chemical Society",

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T1 - Antioxidant principles from Ephemerantha lonchophylla

AU - Chen, Hon Yi

AU - Shiao, Ming Shi

AU - Huang, Yu Lin

AU - Shen, Chien Chang

AU - Lin, Yun Lian

AU - Kuo, Yueh Hsiung

AU - Chen, Chien Chih

PY - 1999/9

Y1 - 1999/9

N2 - One dihydrostilbene and three phenanthrene antioxidants were isolated from an ethanolic extract of the Chinese herbal Ephemerantha lonchophylla. One of these compounds, ephemeranthone (4) is a new natural product. Denbinobin (1) and 3-methylgigantol (3) have been previously isolated from this plant, and 3-ethoxy-5-hydroxy-7-methoxy-1,4-phenanthraquinone (2) is an artifact. The structures of these compounds were determined by spectroscopic analysis. The antioxidative activities for inhibiting human low density lipoprotein oxidation in vitro of compounds 1-4 were determined, and only 4 was active (5.3 times that of probucol).

AB - One dihydrostilbene and three phenanthrene antioxidants were isolated from an ethanolic extract of the Chinese herbal Ephemerantha lonchophylla. One of these compounds, ephemeranthone (4) is a new natural product. Denbinobin (1) and 3-methylgigantol (3) have been previously isolated from this plant, and 3-ethoxy-5-hydroxy-7-methoxy-1,4-phenanthraquinone (2) is an artifact. The structures of these compounds were determined by spectroscopic analysis. The antioxidative activities for inhibiting human low density lipoprotein oxidation in vitro of compounds 1-4 were determined, and only 4 was active (5.3 times that of probucol).

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U2 - 10.1021/np990025f

DO - 10.1021/np990025f

M3 - 文章

C2 - 10514302

AN - SCOPUS:0032828162

SN - 0163-3864

VL - 62

SP - 1225

EP - 1227

JO - Journal of Natural Products

JF - Journal of Natural Products

IS - 9

ER -

Antioxidant principles from Ephemerantha lonchophylla

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