Attachment and migration of cells on porous bone graft

Porous bone graft is prepared using a gel-foaming and sintering technique. The porosity of the bone graft is 70 vol%; the size of pores is around 130 µm. The pores are interconnected through opening of around 40 µm. The interactions between preosteoblast cells and the bone graft are then investigated. Although the pores are interconnected, most the cells are attached to the surface of bone graft. Only a few cells migrate into the cross-section within a time span of 28 days. Such observation provides key information on pore structure design of bone graft.