Auditory Brain Stem Potentials in Chronic Alcohol Intoxication and Alcohol Withdrawal

Nai Shin Chu*, Kenneth C. Squires, Arnold Starr

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

52 Scopus citations


Auditory brain stem evoked responses were studied in unrestrained rats during periods of acute and chronic alcohol intoxication, alcohol withdrawal, and recovery. Acute alcohol administration altered the auditory brain stem potentials by a prolongation of both peak latency and central conduction time, beginning with early peaks. Similar but lesser effects affecting only the latter peaks were observed during chronic alcohol intoxication. By contrast, alcohol withdrawal resulted in a decrease in the peak latencies of auditory brain stem potentials and a facilitation of central conduction time. Recovery of the auditory brain stem potentials to the normal form required at least three to four weeks. The present study provides the first quantitative data, to our knowledge, on manifestations of alcohol tolerance and withdrawal.

Original languageEnglish
Pages (from-to)596-602
Number of pages7
JournalArchives of Neurology
Issue number9
StatePublished - 09 1978
Externally publishedYes


Dive into the research topics of 'Auditory Brain Stem Potentials in Chronic Alcohol Intoxication and Alcohol Withdrawal'. Together they form a unique fingerprint.

Cite this